Gene ML2622c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML2622c
Gene length693 bp
IdentifierML2622c
Location 3132585 bp
Protein summary information
Molecular mass25788.6 Da
Isoelectric point10.66
Protein length231 amino acids
Structural information
PFAMPF02390
Orthologs
M. tuberculosis H37RvRv0208c
M. lepromatosis Mx1-22AMLPM_2622
Cross-references
UniProtQ9CCZ9
Gene OntologyTrna modification, Trna (guanine-n7-)-methyltransferase activity
Enzyme Classification2.1.1.33
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductProbable tRNA (guanine-N(7)-)-methyltransferase (tRNA(m7G46)-methyltransferase )
CommentsML2622c, len: 230 aa. Probable tRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.33). Similar to several e.g. Mycobacterium tuberculosis Rv0208c TR:P96390 (EMBL:Z92669) fasta scores: E(): 0, 64.2% identity in 246 aa, and to Neisseria meningitidis TR:AAF41703 (EMBL:AE002481) fasta scores: E(): 6e-25, 34.9% identity in 232 aa. Belongs to the methyltransferase superfamily. TrmB family.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS31325853133277-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2622c|ML2622c
VARHLPATAFRKRRSALSHAQRQTWERLWPEIGISAVSQTRSAERLDTGAWFGRSTLVVLEVGCGSGTATLAMAQHEPDIDVIAVEVYRRGLAQLLCAIDRDQVHNIRMIHGNALYVLQYLIAPRSLTGVRVFFPDPWPKVRHHKRRFLQPATVELIADRLLPGGVLHTATDHPDYAKQIAKFGDGEPLLSRADGRTQLPISTVRPTTKYETKAQHAGNVVTELIWKKRS
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