Gene ML2634c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namepntB
Gene length1419 bp
IdentifierML2634c
Location 3151473 bp
Protein summary information
Molecular mass48826.1 Da
Isoelectric point6.09
Protein length473 amino acids
Structural information
PFAMPF02233
Orthologs
M. tuberculosis H37RvRv0157
M. lepromatosis Mx1-22AMLPM_2634
Cross-references
UniProtQ9CCZ8
Gene OntologyNadp binding, Integral to membrane, Nad(p)+ transhydrogenase (ab-specific) activity
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE NAD(P) TRANSHYDROGENASE (SUBUNIT BETA) PNTB [INTEGRAL MEMBRANE PROTEIN] (PYRIDINE NUCLEOTIDE TRANSHYDROGENASE SUBUNIT BETA) (NICOTINAMIDE NUCLEOTIDE TRANSHYDROGENASE SUBUNIT BETA)
CommentsML2634c, len: 472 aa. Probable pntB, pyridine transhydrogenase subunit [beta] (EC 1.6.1.1). Similar to Mycobacterium tuberculosis PntB OR Rv0157 TR:P96834 (EMBL:Z92770) fasta scores: E(): 0, 87.3% identity in 473 aa, Rhodospirillum rubrum nicotinamide nucleotide transhydrogenase, subunit beta PntB TR:Q59765 (EMBL:U01158) fasta scores: E(): 0, 46.5% identity in 469 aa and to Escherichia coli NAD PntB SW:PNTB_ECOLI (P07002; P76890) fasta scores: E(): 0, 43.5% identity in 476 aa.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS31514733152891-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2634c|pntB
MNYFVIGLYILAFALFITGLMGLTGPRTAVSGNLIAAVGMTIAVAATLVKIRHTEQWVLIIAALVVGIVLGFPPARLTKVTAMPQLVAFFNGVGGGTVALIALSEFIETSGFSEFQHHESPTVHIVVASLFAAIIGSISFWGSIIAFGKLQETISGFPIGFGKVQQPINLLLLVGAIVAAVVIGLHAQPGSAGASLWWMIGLLVAAGVLGLMVVLSIGGADMPVVISLLNAMTGLSAAATGLALNNTAIIVAGMIVGASGSILTNLMAKAMNRSIPAIVAGGFGSGGVAPSRDGDKQVKSTSAADAAIQMAYANQVIVVPGYGLAVAQAQHVVKDMASLLENKGVPVSYAIHPVAGRMPGHMNVLLAEAEVDYDAMKDMDDINDEFARTDVVIVIGANDVTNPAARNETASPIYGMPILNVDKAKSVIVLKRSMNSGFAGIDNRLFYADGTTMLFGDAKQSVTEVTEELKVL
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