Gene ML2639c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML2639c
Gene length1506 bp
IdentifierML2639c
Location 3157371 bp
Protein summary information
Molecular mass54090.3 Da
Isoelectric point9.64
Protein length502 amino acids
Structural information
PFAMPF00171
Orthologs
M. tuberculosis H37RvRv0147
M. lepromatosis Mx1-22AMLPM_2639
Cross-references
UniProtQ9CCZ5
Gene OntologyCellular aldehyde metabolic process, Aldehyde dehydrogenase [nad(p)+] activity
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE ALDEHYDE DEHYDROGENASE (NAD+) DEPENDENT
CommentsML2639c, len: 501 aa. Probable aldehyde dehydrogenase (EC 1.2.1.-). Similar to many Prokaryotic and Eukaryotic aldehyde dehydrogenases including: Mycobacterium tuberculosis hypothetical 55.0 kda protein Rv0147 TR:P96824 (EMBL:Z92770) fasta scores: E(): 0, 77.1% identity in 493 aa and Homo sapiens aldehyde dehydrogenase, dimeric NADP-preferring ALDH3 SW:DHAP_HUMAN (P30838) fasta scores: E(): 0, 44.7% identity in 450 aa. Contains Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase family. Contains PS00687 Aldehyde dehydrogenases glutamic acid active site.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS31573713158876-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2639c|ML2639c
VLSRRAVGSCGKEEALMITESVAQKTAVSKSGVPPHTPPGVNSEATVVRLRQTFASGRTRSVDWRTQQLRALQALMVENEGAIAQALADDLDRNPVEAFIVDIAATVSEAKYAAKKVRKWMRRKYRFLEVSQLPGRGWVEYEPYGTVLIIGAWNYPFYLTLVPAVGAIAAGNTMVLKPSEVAAASAHLMAELVPRYLDNDAIAVIEGGGAVSQELIAQGLDRVMFTGGTEIGRKVYEGAASHLTPVTLELGGKSPVIVAVDADIDVAAKRIAWIKILNAGQTCVAPDYVLAAAPIRDELVNKIGFAIAKFRSQDDPSGMRIVNQRQFDRLCGYLAGVQSAAGGKGVVVVGGKCDASTLRIQPTVIVDPDPEGPLMTKEIFGPILPVLTVQSLDEAIGFINARPKPLAAYLFTKSRKTRDRVIKEVSAGGMLVNHLAIQVLTAKLPFGGVGESGIGAYHGKWGFDEFSHRKSVLTKPTRPDLSSFIYPPYTERSFRLAHRLF
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