Gene ML2661c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namefadD7
Gene length1647 bp
IdentifierML2661c
Location 3185869 bp
Protein summary information
Molecular mass58329.5 Da
Isoelectric point6.45
Protein length549 amino acids
Structural information
PFAMPF00501
Orthologs
M. tuberculosis H37RvRv0119
M. lepromatosis Mx1-22AMLPM_2661
Cross-references
UniProtQ9CCY8
Gene OntologyMetabolic process, Catalytic activity
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)
CommentsML2661c, len: 548 aa. Probable fadD7, fatty-acid-CoA synthase (EC 6.2.1.-). Similar to many Prokaryotic and Eukaryotic acyl-CoA synthases including: Mycobacterium tuberculosis fadD7 protein Rv0119 TR:O07169 (EMBL:Z96071) fasta scores: E(): 0, 71.3% in 520 aa, and to Saccharomyces cerevisiae peroxisomal-coenzyme a synthetase SW:FAT2_YEAST (P38137) fasta scores: E(): 0, 35.6% in 526 aa. Contains Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme. Contains PS00455 Putative AMP-binding domain signature.
Functional categoryLipid metabolism
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS31858693187515-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2661c|fadD7
MKSESITSSRAPVEQIDARLTGQFESPSIASLVEAAAIRNPSAPALVVTDNRIVVSYRDLLRLVDDLTVQLALGGLLPGDRVALCAASNIEFVVGLLAASRAGLIVVPLDPALPVNEQCIRSQAAGVRVTLVDSLALEGVSDQRAATMRYWPIAVSYGSVTGASEGSLLVHLDDTAALHPVTSTPDGLRHDDAMIMFTGGTTGLPKMVPWTDGNIAGSVHAIITAYQLGPQDATVVVMPLYHGHGLIAALLSTLASGGVVLLPARARFSARTFWDDIDAVAATWYTAAPAIHRILLELASTQSFRSKRAKLRFIRSCSAPLTQETAQALREEFLAPVICAFGMTEATHQVTTTNIKWFGQGENPTVTNGLVGQSTGVQIRIVGSDGQPLPPDTVGEVWLRGSTVVRGYLGDPAITAANFTHGWLRTGDLGSLSVTGDLRIRGRIKELINRSGEKISPERVEGVLASHHNVMEVAVFGDPDKVYGETVTAVIVPREVIAPTPSELAVFCRDRLAAFEVPTRFQEASALPHTAKGSLDRRAVAEQFAHRG
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