Gene ML2670c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML2670c
Gene length2001 bp
IdentifierML2670c
Location 3197970 bp
Protein summary information
Molecular mass73279.9 Da
Isoelectric point9.81
Protein length667 amino acids
Structural information
PFAMPF01757
Orthologs
M. tuberculosis H37RvRv0111
M. lepromatosis Mx1-22AMLPM_2670
Cross-references
UniProtQ9CCY5
Gene OntologyTransferase activity, transferring acyl groups other than amino-acyl groups
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE TRANSMEMBRANE ACYLTRANSFERASE
CommentsML2670c, len: 666 aa. Possible transmembrane acyltransferase (EC 2.3.1.-). Similar to Mycobacterium tuberculosis transmembrane acetyltransferase TR:O53633 (EMBL:AL021926) fasta scores: E(): 0, 78.6% in 681 aa. Also similar to Salmonella typhimurium OafA, a member of the integral membrane trans-acylases TR:P74874 (EMBL:U65941) fasta scores: E(): 7.9e-16, 25.2% in 658 aa. Contains multiple possible membrane spanning hydrophobic domains. Contains 2 Pfam matches to entry PF01757 DUF33, Domain of unknown function.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS31979703199970-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2670c|ML2670c
VRRVGLLRIWNQPERRNGIPALDGLRAIAVALVLTQHGGIPGLSGGFIGVDLFFVLSGFLITSLLLDELRHTGRIDAINFWIRRACRLLPALVLMVLTVGIARELFPYQALTNLRNDAIATFLWVANWRFVVHKADYFTQGTPPSPLQHAWSLGVEEQYYLVWPLLLIAVTLLLAARARRRCRYATLGAVRLAVFVLASLGALASATVAIARVCDVTRDRIYFGTDTRAQALLVGAAASALLVRDWPSLNRGWCLIRTRWGQLIARFLPVLGLAGLAAATHYATGGAGDFRHGLLIGVAIAAVIVIAPVALEQRGTVARLLALRPLVWLGTISYGIYLWHWPIFLALNGERTGWSGVPLFASRCSATVAVAAVSWWLIEQPIRHWRPVRVPLLPLAAATVASAAAATMWVIPVGTETGLRDIALPPEVSTVAAVSPSPPRGKLSSTRDPNQPFTVAVFGDSIGWTWMHYLPPTPGFAFIDHTVIGCSLVRGTPYQYIGQTLEQRPECDNWPIRWSTQINKDHPNVALLIIGRWETVNRVNEGQWTHIGDPTFDSYLNAELQQALNILGSSGVRVVVATVPYSRGGEKPDGQLYPEDQPDRVNQWNTMLRNTVSQHSNVQILDLNKKLCPDGVYTAKVDGIKVRSDGVHLTPEGVKWLTPWLEESLK
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