Gene ML2672c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameicd2
Gene length2241 bp
IdentifierML2672c
Location 3210656 bp
Protein summary information
Molecular mass82761.5 Da
Isoelectric point6.47
Protein length747 amino acids
Structural information
PFAMPF03971
Orthologs
M. tuberculosis H37RvRv0066c
M. lepromatosis Mx1-22AMLPM_2672
Cross-references
UniProtO53115
Gene OntologyTricarboxylic acid cycle, Isocitrate dehydrogenase (nadp+) activity
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE ISOCITRATE DEHYDROGENASE [NADP] ICD2 (OXALOSUCCINATE DECARBOXYLASE) (IDH) (NADP+-SPECIFIC ICDH) (IDP)
CommentsML2672c, len: 746 aa. Probable icd2, isocitrate dehydrogenase [NADP] (EC 1.1.1.42). Similar to Vibrio sp isocitrate dehydrogenase [NADP] 2 SW:IDH2_VIBA1 (P41561) fasta scores: E(): 0, 59.6% in 741 aa and to Mycobacterium tuberculosis Rv0066c isocitrate dehydrogenase TR:O53611 (EMBL:AL021428) fasta scores: E(): 0, 85.4% in 745 aa.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS32106563212896-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2672c|icd2
MSAEQWTIIYTLTDEAPLLATYAFLPIVRAFTKPAGIKVQTSDISVAARILAEFPDYLTEEQRVPNNLAELGRLTQLPDTNIIKLPNISASVPQLMAAIKELQAKGFKLPDYPQDPKSYQEIDIRNRYGKCLGSAVNPVLREGNSDRRAPKAVKEYARNNPHSMGEWSMASRTHVATMRHGDFYHGEKSMTLDRARDVKMELATKKGKIVVLKPKVSLRDGDIIDSMFMSKKALCEFYEEQMEDARKTGVMFSLHVKATMMKVSHPIVFGHAVKTFYKEAFAKHQDLFDELGVNVNNGLVDLYSKIETLTASQRDEIIQDLHACHEHRPELAMVDSARGISNFYSPSDVIVDASMPAMIRAGGKMYGADGRAKDTKAVNPESTFSRIYQEIINFCKTNGAFDPATMGTVPNVGLMAQQAEEYGSHDKTFEIPEDGVANIVDLTTGEVLLTQNVETGDIWRLCVVTDAAIRDWVKLAVSRMRNSGMPVLFWLDPYRPHENELIKKVRAYLKDHDTSGLDIQIMSQVRSMRYTCERLIRGLDTIAATGNILRDYLTDLFPILELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVKQLVEENHLRWDSLGEFLALAVSLEDLGIKTGNERAKILAKTLDVATGKLLDNRKSPSRKAGELDNRGSQFYLAMYWAQELATQTDDQHLRNYFTPLAETLAKNECTIVAELNEAQGKAVDIGGYYAPDAELAKAVMRPSAVFNAALAAAQGS
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