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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN
CommentsML2677, len: 236 aa. Probable transcriptional regulatory protein (TetR-family). Similar to several putative transcriptional regulators including: Mycobacterium tuberculosis transcriptional regulator Rv0078 TR:O53623 (EMBL:AL021428) fasta scores: E(): 0, 71.4% in 175 aa, and Streptomyces coelicolor putative transcriptional regulatory protein TR:CAB76360 (EMBL:AL158061) fasta scores: E(): 0.048, 25.4% in 201 aa. Contains a probable helix-turn-helix motif at aa 35-56 (Score 1329, SD +3.71) Contains Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family.
Functional categoryRegulatory proteins
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS32217043222414+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML2677|ML2677
MESQRRTQEERSTATRDALTLARHRLWRLRGYAEVGTPEIAKEADTTRGAVYHQFTDKAALFRDVVETVEQDAMAQIASVVASSGAKTPVDAIRAKVDAWLEGLADPQVRQLILLYAPSVLGWAAFRDVAQHYSLGMTEQQLLSEASRARQLAQPLDHVLIGKLYESAMAIRRHHRLPEASPARNQTGAAPTHREHVARPSCEALTRHIRHRSTRTRSHRGKRGELLPRAATSSLL
      
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