Gene ML2700 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML2700
Gene length3621 bp
IdentifierML2700
Location 3253066 bp
Protein summary information
Molecular mass126963.0 Da
Isoelectric point8.66
Protein length1207 amino acids
Structural information
PFAMPF03023
Orthologues
M. tuberculosisRv3910
Cross-references
UniProtQ9CCX9
Gene OntologyPathogenesis, Integral to membrane
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE CONSERVED TRANSMEMBRANE PROTEIN
CommentsML2700, len: 1206 aa. Probable conserved transmembrane protein. Similar to Mycobacterium tuberculosis hypothetical 123.6 kda protein Rv3910 TR:O05435 (EMBL:Z94121) fasta scores: E(): 0, 75.1% in 1182 aa. Also the N-terminus is similar to several virulence associated proteins e.g. Salmonella typhimurium virulence factor MviN SW:MVIN_SALTY (P37169) fasta scores: E(): 3e-17, 29.0% in 527 aa. Contains multiple possible membrane spanning hydrophobic domains.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS32530663256686+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2700|ML2700
MKPAPRWTQSQSAQQVTHAMRPCRELSAQQPELSDAALVSRSWAMAFATLISRITGFARVVLLAAILGAALSSAFSVANQLPNLVAALVLEATFTAIFVPVLVRAERSDPDGGTAFVRQLITLTTTLLLLSTTLSVLAAPLLVRLMLGRNPQVNEPLTTAFAYLLLPQVLAYGLSSVFMAILNTRNVFGPPAWAPVINNIVAIAALVGYLVTPGELSVDPVRMGNAKLLVLGIGTTAGAFAQTAVLLVALGREHISLHPLWGLDQRLKRFGAMATAMVLYVLISQLGLVVTNQIASTTAASGPAIYNYTWLVLMLPFGIIGVTVLTVVMPRLSRNAAANDTPAMLADLSLATRLTLITLIPTVAFMTAGGSAMGSVLFAYGHFGEVDAGYLGTAIVLSAFTLIPYGLVLLQLRVFYAREQPWTPIVIIVVITAVRIIVSVLAPYVISNPELVAGYLGMANGLGFAAGAIVGYYLLRRALLPTGGHLFGVQEIRTVLVTIAASLLAGLAAHIADRLLRLNELTMHGGGAGSLLRLTVLTSIMLPTMAVVMLRGHVPEVHAALGAVRGQIMSRNWIAKLQKATVPDQSSRPITVTYPGQNNSSPPRVNAIQESIRSRPPERIAKAQIAKGPEVSDRPVESASSRSASDTGLPSELPRPVAGNSQPYISANLELEHVASLHPPEQQKVDFPAYPARRPIRFEVSRERGGEQSSPTGDVHLVPGACIAGGRYRLLAFHGGAPSLQFWQALDTALDRQVALTFVNPDGALPDDSLQETLSRTLRLSRIDMPGVAQVLDVIHTGSGGLVVSEWIRGGSLHEVADTSPSPVGAIRAMQSLAAAADAAHRAGVALSIDHPSRVRVSTEGDVVLAYPATMPDANHHTDIRGIGATLYALLVNRWPLPEAGMHSGLAPAQQDTTGQPVEPAVIDQNIPTQISAVTVRAVQEDGGILRASTLLNLLQQATAVADRTEVLSPIDDRSPTPTAFCPTTARDPVVFAQRRRNLLIGIGAAVVILVVALLVMASVINKVFGHLGSGLNNDKLGLNTPTSSTSSSPTSSVPEGSIVKPTKATVFSPDGEADNPDDAGLAIDGNPATSWQTDIYNDAVPFPGFKNGVGLMLHLPKPTVVSAVTIDVASIGTKVEIRSASTPTPAKLADTTVLIPATALKPGHNVIEVNSGSPMSNLLVWISTLGSTGGKSLAVISEITIHTPS
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