Gene MMAR_0686
in Mycobacterium marinum M
General annotation
| Type | CDS |
| Function | involved in third step (first of two transformylation reactions) in de novo purine biosynthesis. this is an alternative enzyme to the PurN gar transformylase (5'-phosphoribosylglycinamide formyltransferase). catalyzes two reactions: the first one is the production of beta-formyl glycinamide ribonucleotide (gar) from formate, ATP and beta gar; the second, a side reaction, is the production of acetyl phosphate and ADP from acetate and ATP [catalytic activity: formate + ATP + 5'-phospho-ribosylglycinamide = 5'-phosphoribosyl-N-formylglycinamide + ADP + pyrophosphate]. |
| Product | formate-dependent phosphoribosylglycinamide formyltransferase PurT |
| Comments | - |
| Functional category | Intermediary metabolism and respiration |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 818393 | 819730 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium marinum M|MMAR_0686|purT
VTDGLTEGHDEAIGKHQRPATEGANAPEGDKTTTIAVPPVGTPRRAEADVHVRPRVVLLGGGEQGRELTIALQGLGAEVIAVDTDADAPAHRVADQALVVAMTDADELKVVFTRLRPDFVVPLTDAVSVAALDALADRAPSEGGSIGLVPSARCVRLAGDREALRKLAADQLGLPTAPFWFVGSLGELEAVAAHVGYPLLVKPVAGADVPRRSLVRGPDEVEAAWARAVAGGPAGAPPRVWAETQVEVEFLVTLIAVCSQGPQGPRIDFCAPIGHGGDGGDQESWQPQKVSVAALDAAKSIAARIVKALGGCGVFGVELMVNGDEVYFADVQPFPRDTAWVTLRSQRLSVFELQARAILGFAVDTLMVSPGAARLIGAATVGPVPGADALAAALAVPESDVRVFGRPRAGSSVLGVALATAPDVAVARDRAREVVDRLNVRDSRG
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