Gene MMAR_0716 in Mycobacterium marinum M
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namemutT3
Gene length624 bp
IdentifierMMAR_0716
Location 863151 bp
Protein summary information
Molecular mass22737.6 Da
Isoelectric point5.5
Protein length208 amino acids
Structural information
PFAMB2HPZ8
Orthologs
M. tuberculosis H37RvRv0413
Cross-references
UniProtB2HPZ8
Gene OntologyHydrolase activity
Precomputed results
BLASTReport
General annotation
TypeCDS
Functionpossibly involved in the go system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine) from DNA and the nucleotide pool. 8-OXO-dGTP is inserted opposite da and dc residues of template DNA with almost equal efficiency thus leading to a.T to G.C transversions. mutt specifically degrades 8-OXO-dGTP to the monophosphate [catalytic activity: 8-OXO-dGTP + H2O = 8-OXO-DGMP + pyrophosphate].
Productmutator protein MutT3
Comments-
Functional categoryInformation pathways
Coordinates
TypeStartEndOrientation
CDS863151863774+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium marinum M|MMAR_0716|mutT3
VRGDGDGWVISESGVHYWGRFGSAGLLLRAPRPDGTPAVLLQHRAFWSHQGGTWGLPGGARDSHETPEQTALREAHEEARLPAERLTVRAVTVTARPSGTAWTYTTVIADTRELLHAVPDRESAELRWVAEAEVVDFPLHPGFAASWQGLRCAPVTVPLERGDQRRELLPRTVEVEPGVFVWCMPGDADQVPSQLSPRVISLLEALT
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