Gene MMAR_0742 in Mycobacterium marinum M
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namexthA
Gene length831 bp
IdentifierMMAR_0742
Location 895072 bp
Protein summary information
Molecular mass30338.3 Da
Isoelectric point5.06
Protein length277 amino acids
Structural information
PFAMB2HQN2
Orthologues
M. tuberculosisRv0427c
Cross-references
UniProtB2HQN2
Gene OntologyDna binding, Dna repair, Endonuclease activity, Intracellular
Precomputed results
BLASTReport
General annotation
TypeCDS
Functioninvolved in base excision repair. apurinic-apyrimidinic endonuclease. supposed to remove the damaged DNA at cytosines and guanines by cleaving at the 3' side of the ap site by a beta-elimination reaction. possibly exhibites 3'-5'-exonuclease, 3'-phosphomonoesterase, 3'-repair diesterase and ribonuclease H activities [catalytic activity: degradation of double-stranded DNA. it acts progressively in a 3'- to 5'-direction, releasing 5'-phosphomononucleotides].
Productexodeoxyribonuclease III protein XthA
Comments-
Functional categoryInformation pathways
Coordinates
TypeStartEndOrientation
CDS895072895902-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium marinum M|MMAR_0742|xthA
MPDGTLRLATWNVNSIRTRLPRVLDWLERADVDVLAIQETKCSDTQFPALPLFELGYEVAHVGFNQWNGVAIASRVGIDDVQIGFDGQPAWSGKPEVAAAAEARAVGATCGGVRVWSLYVPNGRALEDPHYTYKLDWLAALRDTAQCWLKNDPGAPIALAGDFNIAPTDEDVWSTEFFTGATHVSEPERKAFNAIVDAQFTDLVRPFTPGPGVYTYWDYTQLRFPKKQGMRIDFILGSPALAGRVVDAQIVRDERKGKAPSDHAPVFVDLRPGPAA
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