Gene MMAR_0880 in Mycobacterium marinum M
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namemenA
Gene length876 bp
IdentifierMMAR_0880
Location 1071081 bp
Protein summary information
Molecular mass29622.9 Da
Isoelectric point10.09
Protein length292 amino acids
Structural information
PFAMB2HRM5
Orthologs
M. tuberculosis H37RvRv0534c
Cross-references
UniProtB2HRM5
Gene OntologyIntegral to membrane, Menaquinone biosynthetic process, Prenyltransferase activity
Precomputed results
BLASTReport
General annotation
TypeCDS
Functioninvolved in menaquinone biosynthesis. conversion of 1,4-dihydroxy-2-naphthoate (DhnA) to dimethylmenaquinone (DMK). attaches octaprenylpyrophosphate, a membrane-bound 40-carbon side chain to DhnA. the conversion of DhnA to DMK proceeds in three stages: the removal of the carboxyl group of DhnA as CO2, the attachment of the isoprenoid side chain, and a quinol-to-quinone oxidation, which is thought to be spontaneous.
Product1,4-dihydroxy-2-naphthoate octaprenyltransferase, MenA
Comments-
Functional categoryIntermediary metabolism and respiration
Coordinates
TypeStartEndOrientation
CDS10710811071956-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium marinum M|MMAR_0880|menA
MVANIAQWISGARPRTLPNAVAPVVAGTGAAAWLHAAVWWKALLALVVAVALTVGVNYANDYSDGIRGTDDDRTGPMRLVGSRLATPRSVLIAAIVSLMIGAAAGLALALASAPWLIAVGAGCIAGAWLYTGGSRPYGYSGLGEVAVFVFFGLVAVLGTQYTQALRVDWVGLALAVATGALSSAVLVANNLRDIPTDAQSHKITLAVRLGDARTRVLYQALLVTAAVLTLALTLATPWCAVGLLATPLALRAAAPVRAGRGGAALIPVLRDTGLAMMVWAIAMSAALALAA
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