Gene MMAR_1277
in Mycobacterium marinum M
General annotation
| Type | CDS |
| Function | involved in GDP-mannose biosynthesis and biosynthesis of nucleotide-activated glycero-manno-heptose (D-alpha-D pathway): generates GDP-mannose and phosphate from GTP and alpha-D-mannose 1-phosphate. ManB product is needed for all mannosyl glycolipids and polysaccharides which, like rhamnosyl residues, are an important part of the mycobacterium envelope [catalytic activity: alpha-D-mannose 1-phosphate + GTP = GDP-mannose + phosphate]. |
| Product | d-alpha-D-mannose-1-phosphate guanylyltransferase ManB |
| Comments | - |
| Functional category | Cell wall and cell processes |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 1559634 | 1560710 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium marinum M|MMAR_1277|manB
LATNGVDAVVLVGGKGTRLRPLTLSAPKPMLPTAGLPFLTHLLSRIAAAGIEHVVLSTSYQAGVFEAEFGDGSKLGLQIDYVTEDKPLGTGGGIVNVAGKLHHDTVMVFNGDVLSGADLGQLLDYHHQNQADVTLHLVRVGDPRAFGCVPTEDGRVTAFLEKTQDPPTDQINAGCYVFKREIIDRIPRGREVSVEREVFPSLLSDPDIKIYGYVDATYWRDMGTPEDFVRGSADLVRGIAPSPALQGQRGEQLVHDGAAIAPGAVLIGGTVVGRGAEIGPGVRLDGAVIFDGVKVEAGSVIERSIIGFGARIGPRALVRDGVIGDGADIGARCELLRGARVWPGVSIPDGGIRYSSDV
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