Gene MMAR_1642 in Mycobacterium marinum M
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namenrdE
Gene length2166 bp
IdentifierMMAR_1642
Location 1986947 bp
Protein summary information
Molecular mass82060.7 Da
Isoelectric point5.97
Protein length722 amino acids
Structural information
PFAMB2HHG0
Orthologs
M. tuberculosis H37RvRv3051c
Cross-references
UniProtB2HHG0
Gene OntologyAtp binding, Dna replication, Oxidation-reduction process, Protein binding, Ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor, Ribonucleoside-diphosphate reductase complex
Enzyme Classification1.17.4.1
Precomputed results
BLASTReport
General annotation
TypeCDS
Functioninvolved in the DNA replication pathway. catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides, precursors that are necessary for DNA synthesis. [catalytic activity: 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H(2)O = ribonucleoside diphosphate + reduced thioredoxin].
Productribonucleoside-diphosphate reductase (alpha chain) NrdE
Comments-
Functional categoryInformation pathways
Coordinates
TypeStartEndOrientation
CDS19869471989112+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium marinum M|MMAR_1642|nrdE
VSPTVTAEPVTTSAHALPGETDYHALNAMLNLYDADGKIQFDRDVLAARQFFLQHVNQNTVFFHNQDEKLDYLIRENYYEREVLDQYSRNFVKTLLDRAYAKKFRFPTFLGAFKYYTSYTLKTFDGKRYLERFEDRVVMVALTLASGDATLAEKLVDEIIDGRFQPATPTFLNSGKKQRGEPVSCFLLRIEDNMESIGRSINSALQLSKRGGGVALLLTNIREHGAPIKNIENQSSGVIPIMKLLEDSFSYANQLGARQGAGAVYLHAHHPDIYRFLDTKRENADEKIRIKTLSLGVVIPDITFELAKRNDDMYLFSPYDVERVYGVPFADISVTEKYYEMVDDSRIRKTKIKAREFFQTLAELQFESGYPYIMFEDTVNRANPIEGKITHSNLCSEILQVSTPSLFNDDLSYAKVGKDISCNLGSLNIARTMDSPDFAQTIEVAIRALTAVSDQTHITSVPSIEQGNNDSHAIGLGQMNLHGYLAREHIFYGSEEGVDFTNIYFYAVLYHALRASNRIAVERGTRFKGFDQSKYASGEFFDKYTERVWEPKTEKVRQLFADAGIRIPNQDDWQRLKESVQAHGIYNQNLQAVPPTGSISYINHSTSSIHPIVSKVEIRKEGKIGRVYYPAPYMTNENLDYYQDAYEIGYEKIIDTYAAATEHVDQGLSLTLFFKDTATTRDVNKAQIYAWRKGIKTLYYIRLRQMALEGTEVAGCVSCML
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