Gene MMAR_1647 in Mycobacterium marinum M
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namenrdF2
Gene length975 bp
IdentifierMMAR_1647
Location 1992809 bp
Protein summary information
Molecular mass36909.3 Da
Isoelectric point4.58
Protein length325 amino acids
Structural information
PFAMB2HHG5
Orthologs
M. tuberculosis H37RvRv3048c
Cross-references
UniProtB2HHG5
Gene OntologyDeoxyribonucleoside diphosphate metabolic process, Ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor, Transition metal ion binding
Precomputed results
BLASTReport
General annotation
TypeCDS
Functioninvolved in the DNA replication pathway. catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides, precursors that are necessary for DNA synthesis [catalytic activity: 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H(2)O = ribonucleoside diphosphate + reduced thioredoxin].
Productribonucleoside-diphosphate reductase (beta chain) NrdF2
Comments-
Functional categoryInformation pathways
Coordinates
TypeStartEndOrientation
CDS19928091993783+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium marinum M|MMAR_1647|nrdF2
VTGNAKLIDRVSAINWNRVQDEKDAEVWDRLTGNFWLPEKVPVSNDIPSWGTLTAGEKQLTMRVFTGLTMLDTIQGTVGAVSLIPDALTPHEEAVLTNIAFMESVHAKSYSQIFSTLCSTAEIDDAFRWSEENSNLQRKAEIVLEYYRGDDPLKRKVASTLLESFLFYSGFYLPMYWSSRAKLTNTADMIRLIIRDEAVHGYYIGYKFQRGLAAADEARRTELKDYTYELLFELYDNEVEYTQDLYDEVGLTEDVKKFLRYNANKALMNLGYEALFPRDETDVNPAILSALSPNADENHDFFSGSGSSYVIGKAVVTQDEDWDF
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