Gene MMAR_1783 in Mycobacterium marinum M
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namefpg
Gene length879 bp
IdentifierMMAR_1783
Location 2175510 bp
Protein summary information
Molecular mass31885.4 Da
Isoelectric point9.44
Protein length293 amino acids
Structural information
PFAMB2HJJ6
Orthologs
M. tuberculosis H37RvRv2924c
Cross-references
UniProtB2HJJ6
Gene OntologyBase-excision repair, Damaged dna binding, Nucleotide-excision repair, Oxidized purine nucleobase lesion dna n-glycosylase activity, Zinc ion binding
Enzyme Classification4.2.99.18, 3.2.2.23
Precomputed results
BLASTReport
General annotation
TypeCDS
Functioninvolved in base excision repair (repair of oxidized purines). this enzyme may play a significant role in processes leading to recovery from mutagenesis and/or cell death by alkylating agents [catalytic activity hydrolysis of DNA containing ring-opened N7-methylguanine residues, releasing 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimide].
Productformamidopyrimidine-DNA glycosylase Fpg
Comments-
Functional categoryInformation pathways
Coordinates
TypeStartEndOrientation
CDS21755102176388+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium marinum M|MMAR_1783|fpg
MPELPEVEVVRRGLQDHVVGKTMTAVRVHHPRAVRRHEAGPADLTARLLGARISGTDRRGKYLWLTLDAGAPTTGRDDPDTALVVHLGMSGQMLLGGVPRAEHVRISAVLDDGTVLSFADQRTFGGWQLADLVSVDGSVVPAPVAHLARDPLDPLFDVDSVIKVLRGKHSEIKRQLLDQQVVSGIGNIYADEALWRAKVHGARVAATLTRRQLGAVLDAAADVMREALAKGGTSFDSLYVNVNGQSGYFDRSLDAYGREGEHCRRCGAVMRREKFMNRSSFYCPRCQPRPRR
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