Gene MMAR_2257 in Mycobacterium marinum M
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameotsB1
Gene length3657 bp
IdentifierMMAR_2257
Location 2716209 bp
Protein summary information
Molecular mass135498.0 Da
Isoelectric point5.52
Protein length1219 amino acids
Structural information
PFAMB2HPA2
Orthologs
M. tuberculosis H37RvRv2006
Cross-references
UniProtB2HPA2
Gene OntologyCarbohydrate binding, Catalytic activity, Trehalose biosynthetic process
Precomputed results
BLASTReport
General annotation
TypeCDS
Functioninvolved in trehalose biosynthesis (protective effect). mycobacteria can produce trehalose from glucose 6-phosphate and UDP-glucose (the OtsA-OtsB pathway) from glycogen-like alpha(1-->4)-linked glucose polymers (the TreY-TreZ pathway) and from maltose (the TreS pathway). seems to have additional alpha-glucosidase activity.
Producttrehalose-6-phosphate phosphatase OtsB1
Comments-
Functional categoryUnknown
Coordinates
TypeStartEndOrientation
CDS27162092719865+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium marinum M|MMAR_2257|otsB1
MKSFTIDPRRHDGVIFVLDGDGHEQSIWEPTVALARKLWQVGVGTAVYSPTDESVRVLDAAGLSEPEQVSAPPQASRAKPYCVGLSAAAAKLGAAVQRLAVVAGMDGGVEAARECGFAFVIGFDRDGRAEELLRRGADVVAADLAEVTVRTGDERLSQCPNALDSYGQVIGMVAGRQLFVCMDYDGTLSEIVSEPDAATLVDGAAEALAHLSTQCPVAILSGRDLTDIRDRVGVPGIWYAGSHGFELIAPDGTHHQHEAAAAAVDVLASAAKDLRHELAQIPGVSVEHKRFGVAVHYRNVAREHVAQVIATTHRYRREYGLRVTSGRKVVELRPDIDWDKGAALAWIRSLIFEDSRVLPMYVGDDLTDEDAFDALRFSGVGIVVRHDEDGDRPTAANFTLRNPNEVRDFVRRGAGWLAHAHETQSRGWTFTFEGYDPPNEKLREALCTVGNGYFATRGAAPESKAGQVHYPGTYAGGVFNRLDDLIGGTRTAHESLVNLPNWLPLTFRIDGGDWFDVDAVTLLSYRQTLDLRGAVLTRELTFRDDAGRTSSVTQHRFVSMNQAHVAALQTTIVGHDWSGTIEIRSTIDGNVRNSGVERYRNLASNHLQGLQKAVLSENSVSMAVETTQSKIPVAVAARTSLWRADEPVAATYRLLDEEFEIGHEIFTEAKLGQPLTVEKIVTLVSGLDVATSHPAIGAERRLGRQGRFAEICDAHRIAWSHLWERLSIEFSNHTEELRVLRLHLLHLLQTVSYNSADLDVGVPARGLHGEAYRGHIFWDELFIFPVLNLRLPAVTRSLLLYRYRRLLEAQRAAKLAGYRGAMYPWQSGSDGREESPEQHLNPRSGRWIPDASHRAHHIGIAVAYNVWQFYQVTGDLAFMIDYGTEMMAEIARFWVSRATYDAERDRYHIKGVIGPDEFHSGYPDRPYDGVDDNAYTNVMAAWVILRAIDALLLMPLPNRLDLYEKLALTEEELAQWDHVSRRMFVPFHDGVISQFDGYEQLAELDWDAYRQRYGNIQRLDRILEAEDDDVNRYRASKQADALMLLYLLSADELGELLDRLGYHMERDQIPEMVDYYMARTSHGSTLSAAVHGWVLARANRDRALEFFQQVLESDVADIQGGTTAEGVHLAAMAGSVDFVQRCFTGLEIRADRIVLSPHWPEYLGALGFPIHYRGNHLHLRVSGKGAEISVEPRDVPPVEVECHGRVERLLPGSTVRFS
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