Gene MMAR_2374 in Mycobacterium marinum M
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameilvA
Gene length1281 bp
IdentifierMMAR_2374
Location 2865103 bp
Protein summary information
Molecular mass44949.0 Da
Isoelectric point4.69
Protein length427 amino acids
Structural information
PFAMB2HQ80
Orthologs
M. tuberculosis H37RvRv1559
Cross-references
UniProtB2HQ80
Gene OntologyL-threonine ammonia-lyase activity, Isoleucine biosynthetic process, Pyridoxal phosphate binding
Precomputed results
BLASTReport
General annotation
TypeCDS
Functioninvolved in isoleucine biosynthesis (first step). catalyzes the formation of alpha-ketobutyrate from threonine in a two step reaction. the first step is a dehydration of threonine, followed by rehydration and liberation of ammonia [catalytic activity : L-threonine + H(2)O = 2-oxobutanoate + NH(3) + H(2)O]
Productthreonine dehydratase IlvA
Comments-
Functional categoryIntermediary metabolism and respiration
Coordinates
TypeStartEndOrientation
CDS28651032866383+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium marinum M|MMAR_2374|ilvA
VSAELSQTPSRSPLSAADIDNAAERIAPVITPTPLQLCERLSDITGATVYLKREDLQIVRSYKLRGAYNLLVQLTAEELAAGVVCSSAGNHAQGFAFACKTLGVHGRVYVPAKTPKQKRDRIRYHGGEFIDLIVGGETYDLAAAAAREDVERTGATLVPPYDDLRTMAGQGTIAVELLAELDAEPDLVVVPVGGGGCIAGITSYLAERTTKTAVLGIEPAGAAAMMAALAAGEPVTLDHVDQFVDGAAVNRAGTLPYAALSAAGDMVSITTVDEGAVCTAMLDLYQHEGIIAEPAGALSVAGLLEADIEPGSTVVCLISGGNNDVSRYGEILERSLVHLGLKHYFLVDFPQEPGALRRFLDEVLGPNDDITLFEYVKRNNRETGEALVGVELGSAANLDGLLARMHETEVHVEPLAPGSPAYRYLL
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