Gene MMAR_2411 in Mycobacterium marinum M
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nametrpE
Gene length1539 bp
IdentifierMMAR_2411
Location 2909683 bp
Protein summary information
Molecular mass55375.5 Da
Isoelectric point4.81
Protein length513 amino acids
Structural information
PFAMB2HQX5
Orthologues
M. tuberculosisRv1609
Cross-references
UniProtB2HQX5
Gene OntologyAnthranilate synthase activity, Tryptophan biosynthetic process
Precomputed results
BLASTReport
General annotation
TypeCDS
Functioninvolved in tryptophan biosynthesis pathway (at the first step). supposed tetramer of two components I and two components II: component I TrpE) catalyzes the formation of anthranilate using ammonia rather than glutamine, whereas component II (TrpG) provides glutamine amidotransferase activity [catalytic activity: chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate].
Productanthranilate synthase component I TrpE
Comments-
Functional categoryIntermediary metabolism and respiration
Coordinates
TypeStartEndOrientation
CDS29096832911221+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium marinum M|MMAR_2411|trpE
MRADLATTITRENFRSLAAEHRVVPVTRKVLADSETPLSAYRKLADGRPGTFLLESAENGRSWSRWSFIGAGAPTALTVRDGEAVWLGTAPEGAPTGGDPLRALQSTLEVLATGVMPGLPPLSGGMVGFFAYDMVRRLERLPNLAVDDLQLPEMLLLLATDLAAVDHHEGTITLIANAVNWDGTDERVDWAYDDAIARLDVMTAALSQPLPSSVATFSRPEPHYRAQRTVEEYGAIVEHLVEEIAAGEAFQVVPSQRFEMDTTVDPIDVYRILRVTNPSPYMYLIQVPNDHGSVEFSIVGSSPEALVTVHDGCATTHPIAGTRWRGETDEEDQLLEKELLADQKELAEHLMLVDLGRNDLGRVCIPGTVRVEDYSHIERYSHVMHLVSTVTGLLDAGHSALDAVTACFPAGTLSGAPKVRAMELIEEMEKTRRGLYGGVVGYLDFAGNADFAIAIRTALMRNGTAYVQAGGGVVADSNGPYEYNEARNKARAVLNAIAAAETLARPDAACSD
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