Gene MMAR_2415 in Mycobacterium marinum M
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nametrpA
Gene length810 bp
IdentifierMMAR_2415
Location 2914133 bp
Protein summary information
Molecular mass27976.5 Da
Isoelectric point4.89
Protein length270 amino acids
Structural information
PFAMB2HQX9
Orthologs
M. tuberculosis H37RvRv1613
Cross-references
UniProtB2HQX9
Gene OntologyTryptophan biosynthetic process, Tryptophan synthase activity
Enzyme Classification4.2.1.20
Precomputed results
BLASTReport
General annotation
TypeCDS
Functiontryptophan biosynthesis pathway (fifth - last step). the alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate. [catalytic activity: L-serine + 1-(indol-3-YL)glycerol 3-phosphate = L-tryptophan + glyceraldehyde 3-phosphate + H(2)O.].
Producttryptophan synthase, alpha subunit TrpA
Comments-
Functional categoryIntermediary metabolism and respiration
Coordinates
TypeStartEndOrientation
CDS29141332914942+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium marinum M|MMAR_2415|trpA
MTVEQREASRLGPLFDSCRAENRAALIGYLPTGYPDVNTSVRAMTELVESGCDIVEVGVPYSDPGMDGPTIQRATEAALSGGVRVRDALTAVESISKAGGRAVVMTYWNPVLRYGVDAFARDLAAAGGHGLITPDLIPDEAQQWLAASDEHGLDRIFLVAPSSTPERLANTVAASRGFVYAASTMGVTGARDAVSNAAPDLVARVKAVSDIPVGVGLGVRSREQAAEIGRYADGVIVGSALVSALGDGLPSLRSLTEELAAGVRQRNSP
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