Gene MMAR_3764 in Mycobacterium marinum M
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameproB
Gene length1107 bp
IdentifierMMAR_3764
Location 4642271 bp
Protein summary information
Molecular mass37880.0 Da
Isoelectric point6.08
Protein length369 amino acids
Structural information
PFAMB2HMG0
Orthologues
M. tuberculosisRv2439c
Cross-references
UniProtB2HMG0
Gene OntologyAtp binding, Rna binding, Cytoplasm, Glutamate 5-kinase activity, Proline biosynthetic process
Enzyme Classification2.7.2.11
Precomputed results
BLASTReport
General annotation
TypeCDS
Functioninvolved in proline biosynthesis pathway (at the first step). catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5-oxoproline [catalytic activity: ATP + L-glutamate = ADP + L-glutamate 5- phosphate].
Productglutamate 5-kinase protein ProB
Comments-
Functional categoryIntermediary metabolism and respiration
Coordinates
TypeStartEndOrientation
CDS46422714643377-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium marinum M|MMAR_3764|proB
MGSPHREAIRTARSVVVKVGTTALTTPSGVFDAGRLAELADAIESRMKAGTDVVIVSSGAIAAGIEPLGLSRRPKDLATKQAAASVGQVALVNSWSAAFARYGRTVGQVLLTAHDIAMRVQHSNAQRTLDRLRALHAVGIVNENDTVATNEIRFGDNDRLSALVAHLVGADALVLLSDIDGLYDADPGKFQNARFIPEVSGPADLDGVVAGQGSHLGTGGMASKMSSALLAADAGVPVLLAPAADAAAALTDASVGTVFAARSERMSARRFWVRYAAESAGSLTLDEGAVRAVVGHRRSLLPAGITAVAGKFFGGDVVDLCGPDATMVARGVVAYDATELATMMGRSTSELPGELRRPAVHADDLVAV
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