Gene MMAR_3771 in Mycobacterium marinum M
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namefolC
Gene length1455 bp
IdentifierMMAR_3771
Location 4650043 bp
Protein summary information
Molecular mass50590.1 Da
Isoelectric point4.57
Protein length485 amino acids
Structural information
PFAMB2HMG7
Orthologues
M. tuberculosisRv2447c
Cross-references
UniProtB2HMG7
Gene OntologyAtp binding, Folic acid-containing compound biosynthetic process, Tetrahydrofolylpolyglutamate synthase activity
Precomputed results
BLASTReport
General annotation
TypeCDS
Functionconversion of folates to polyglutamate derivatives. bacteria require folate for the biosynthesis of glycine, methionine, formyl-met-tRNA, thymidylates, purines, and pantothenate [catalytic activity: ATP + {tetrahydrofolyl-[Glu]}(N) + L-glutamate = ADP + phosphate + {tetrahydrofolyl-[Glu]}(n+1)].
Productfolylpolyglutamate synthase protein FolC
Comments-
Functional categoryIntermediary metabolism and respiration
Coordinates
TypeStartEndOrientation
CDS46500434651497-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium marinum M|MMAR_3771|folC
MSFDPPDWTGLAQGSDAEPTPDELASLLQVEHLLDQRWPETRIEPSLTRISALMDLLGSPQLSYPSIHIGGTNGKTSVARMVDALITALHQRTGRTTSPHLQSAVERISIDGKPITPAQYVQTYREIEPFVQMIDQQSQAAGGPAMSKFEVLTAMAFAAFADAPVDVAVVEVGLGGRWDATNVINAPVAVITPISIDHVDYLGDDIASIAGEKAGIIHKAADGSPDTVAVIGRQLPEAMEVLLAQAVRADAAVAREDSEFAVLGRQVAVGGQLLQLQGLGGVYSDIYLPLHGEHQAHNAVVALAAVEAFFGAGAQRQLDVDAVRAGFAAVTSPGRLERLRSSPTVFIDAAHNPAGAAALAQSLVAEFDFRSLVGVIAVMADKDVNGILAALEPAFDSIVVTHNGSPRALDVASLALAAEQYFGPDRVITAENLRDAVDAATALVDESAIDWEAQGGSLSGTGIVITGSVVTAGAARTLFGRDPQ
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