Gene MMAR_3823 in Mycobacterium marinum M
Go to browser
virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameplcB_1
Gene length1557 bp
IdentifierMMAR_3823
Location 4746806 bp
Protein summary information
Molecular mass56120.5 Da
Isoelectric point6.12
Protein length519 amino acids
Structural information
PFAMB2HNI0
Orthologs
M. tuberculosis H37RvRv2350c
Cross-references
UniProtB2HNI0
Gene OntologyHydrolase activity, acting on ester bonds
Precomputed results
BLASTReport
General annotation
TypeCDS
Functionhydrolyzes sphingomyelin in addition to phosphatidylcholine. probable virulence factor implicated in the pathogenesis of mycobacterium tuberculosis at the level of intracellular survival, by the alteration of cell signaling events or by direct cytotoxicity [catalytic activity: a phosphatidylcholine + H(2)O = 1,2- diacylglycerol + choline phosphate].
Productmembrane-associated phospholipase C 2 PlcB_1
Comments-
Functional categoryVirulence, detoxification, adaptation
Coordinates
TypeStartEndOrientation
CDS47468064748362+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium marinum M|MMAR_3823|plcB_1
VSKSPVDAMSRREFLAKAAAASGAGAFMSLAGPVIEKAYAAGPCSGHLSDIEHIVLFMQENRSFDHYFGKLSGTNGFDSGSPLFAQKGWNPQTQSNDPAGTTIPYRFDTTRGPLVAGECVNDPGHDWIAMHNAWNNGGNDNWLPAQAAVSALQGNTPVTMGYYQREDIPIHYLLADTFTICDGYFCSLIGGTSPNRLYWMSGTIDPDGANGGPLLVDPNIQPQGRFSWRTMPDNLEDAGVSWKIYQNKLLGALNNTVIGYDGMLNDFKQAQNPRTNLARYGIAPTYPRDFVSDVRNNRLPKVSWVLPGFLLSEHPAFPVNVGAVAIVDVLRILLSNPAVWEKTALIVSYDENGGFFDHVTPTTAPPGTPGEWITVPNIDAVTGSGGIRGPIGLGYRVPCFVISPYSRGPLMVHDTFDHTSQLKLIETRFGVPVPNISAWRNGLVGDMTSTFNFAVPPNSSRPNLSHPAINAVQKLPQCVPNYVLGTVTKTAVPYRVPFPQVMPTQETQPARGIPSGLC
Bibliography
No article yet recorded