Gene MMAR_4290 in Mycobacterium marinum M
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namemutT2
Gene length591 bp
IdentifierMMAR_4290
Location 5285401 bp
Protein summary information
Molecular mass21195.6 Da
Isoelectric point9.22
Protein length197 amino acids
Structural information
PFAMB2HSB8
Orthologs
M. tuberculosis H37RvRv1160
Cross-references
UniProtB2HSB8
Gene OntologyHydrolase activity
Precomputed results
BLASTReport
General annotation
TypeCDS
Functioninvolved in the go system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine) from DNA and the nucleotide pool. 8-OXO-dGTP is inserted opposite da and dc residues of template DNA with almost equal efficiency thus leading to at to Gc transversions. mutt specifically degrades 8-OXO-dGTP to the monophosphate.
Productmutator protein MutT2
Comments-
Functional categoryInformation pathways
Coordinates
TypeStartEndOrientation
CDS52854015285991-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium marinum M|MMAR_4290|mutT2
LRAIMFGLSKPAWRAVKAAVAQGWGVLGQHGFGRIAVRRIWEVALPGRLGEIPSLAMPNQPNQIVVAGAIIRGATVLVAQRARPPELAGRWELPGGKVAGGETEPAALARELVEELGLGVDDVAVGERLGADVVLDEKTVLRAYRVRLLRGHPCARDHRALRWVTADQLDDVDWVPADRCWLADLDRALRPAPPPG
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