Gene MMAR_4481 in Mycobacterium marinum M
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namemetS
Gene length1557 bp
IdentifierMMAR_4481
Location 5503341 bp
Protein summary information
Molecular mass57958.3 Da
Isoelectric point5.27
Protein length519 amino acids
Structural information
PFAMB2HDK3
Orthologues
M. tuberculosisRv1007c
Cross-references
UniProtB2HDK3
Gene OntologyAtp binding, Cytoplasm, Methionine-trna ligase activity, Methionyl-trna aminoacylation
Precomputed results
BLASTReport
General annotation
TypeCDS
Functionit is probably essential for cell survival, being required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation [catalytic activity: ATP + L-methionine + tRNA(met) = AMP + diphosphate + L-methionyl-tRNA(met)]
Productmethionyl-tRNA synthetase MetS
Comments-
Functional categoryInformation pathways
Coordinates
TypeStartEndOrientation
CDS55033415504897+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium marinum M|MMAR_4481|metS
MKPYYVTTAIAYPNAAPHVGHAYEYIATDAIARFKRLDGFDVRFLTGTDEHGLKVAQAAAAAEIPTAQLARRNSDVFQRMQEALNISFDRFIRTTDADHYEASQEIWRRMDAAGDIYLDSYSGWYSVRDERFFVESETQVVDGTRIATETGTPVTWTEEQTYFFRLSAYADKLLAHYEANPDFIAPEVRRNEVVSFVSGGLKDLSVSRTSFNWGVPVPGHPDHVMYVWVDALTNYLTGAGYPDTGSEAFLRYWPADLHMIGKDIIRFHAVYWPAFLMSAGIELPRRVFAHGFLHNRGEKMSKSLGNTIDPMGLIETYGVDQVRYFLLREVPFGQDGSYSEEAIINRINTDLANELGNLAQRSLSMIAKNLGGAVPEPGEFSAADRELLAIADGLLERVREHFDNQSMHLALEAIWLMLGHANKYFSDQQPWVLRKSESEADQARFRTTLYTTCEAVRIAALLVAPVMPESAAKLLDLLGQGPDQRSFNAIGARLVPGTAMPSPTGVFPRYQPPPSETG
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