Gene MMAR_4932 in Mycobacterium marinum M
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namecyp51B1
Gene length1371 bp
IdentifierMMAR_4932
Location 5991766 bp
Protein summary information
Molecular mass52368.3 Da
Isoelectric point5.54
Protein length457 amino acids
Structural information
PFAMB2HH81
Orthologs
M. tuberculosis H37RvRv0764c
Cross-references
UniProtB2HH81
Gene OntologyElectron carrier activity, Heme binding, Monooxygenase activity
Precomputed results
BLASTReport
General annotation
TypeCDS
Functioninvolved in sterol biosynthesis. its biological substrate is not known. catalyzes C14-demethylation of lanosterol, 24,25-DIHYDROLANOSTEROL and obtusifoliol which is critical for ergosterol biosynthesis. it transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol.
Productcytochrome P450 51B1 Cyp51B1
Comments-
Functional categoryIntermediary metabolism and respiration
Coordinates
TypeStartEndOrientation
CDS59917665993136+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium marinum M|MMAR_4932|cyp51B1
VTTAIVPRVSGGEEEHGHLEEFRTDPIGLMQRVRDECGDVGWFQLANKHVVLLSGAKANEFFFRSSDEELDQAEAYPFMTPIFGKGVVFDASPERRKEMLHNSALRGEHMKGHATTIEREVHRMIENWGQEGEIDLLEFFAELTIYTSTSCLIGTKFRNQLDSRFAHFYHELERGTDPLCYVDPYLPIESFRRRDEARKGLVALVQDIMHQRVANPPTDKRDRDMLDVLVSITDEQGNPRFCADEVTGMFISLMFAGHHTSSGTSAWTLIELLRHPDAYAAVIDELDELYADGQPVSFHALRQIPRLENVLKETLRLHPPLIILMRVAKGEFQVEGYPIHEGELVAASPAISNRIAEDFPDPDEFVPERYQEPRQEDLINRWTWIPFGAGRHRCVGAAFATMQIKAIFSVLLREYEFEMAQPADSYRNDHSKMVVQLARPARVRYRRRKMSDNRGH
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