Gene MMAR_4978 in Mycobacterium marinum M
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameotsA
Gene length1503 bp
IdentifierMMAR_4978
Location 6042239 bp
Protein summary information
Molecular mass56113.7 Da
Isoelectric point6.18
Protein length501 amino acids
Structural information
PFAMB2HHY2
Orthologs
M. tuberculosis H37RvRv3490
Cross-references
UniProtB2HHY2
Gene OntologyTransferase activity, transferring glycosyl groups, Trehalose biosynthetic process
Enzyme Classification2.4.1.-
Precomputed results
BLASTReport
General annotation
TypeCDS
Functioninvolved in osmoregulatory trehalose biosynthesis. mycobacteria can produce trehalose from glucose 6-phosphate and UDP-glucose (the OtsA-OtsB pathway) from glycogen-like alpha(1-->4)-linked glucose polymers (the TreY-TreZ pathway) and from maltose (the TreS pathway) [catalytic activity: trehalose 6-phosphate + H(2)O = trehalose + orthophosphate].
Productalpha, alpha-trehalose-phosphate synthase [UDP-forming] OtsA
Comments-
Functional categoryIntermediary metabolism and respiration
Coordinates
TypeStartEndOrientation
CDS60422396043741+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium marinum M|MMAR_4978|otsA
MGPGGRQSAEPASTEVFGDSDFVVVANRLPVDQERLPDGTIAWKRSPGGLVTALEPLLRRRRGAWVGWAGVVENDVDVQDEPIVQDELQLQPVRLSADDVAQYYEGFSNATLWPLYHDVIVRPIYHREWWDRYVDVNRRFAEATARAAARGGTVWVQDYQLQLVPKMLRAMRPDLTIGFFLHIPFPPVELFMQLPWRTEIIQGLLGADLVGFHLPGGAQNFLILSRRLVGADTSRGTVGVRSRFGEVILGSRTIRVGAFPISIDSGALDQTARDRNIRRRSREIRAELGNPRKILLGVDRLDYTKGIDVRLKAFSELLAEGRVKRDDTVLVQLATPSRERVESYQTLRNDIERQVGHINGEYAEVGHPVVHYLHRPVPRNELIAFFVASDVMLVTPLRDGMNLVAKEYVACRSDLGGALVLSEFTGAAAELRHAYLVNPHDLEGVKDGIEEALNQTEEAGRRRMRSMRRQVLAHDVDRWARSFLDALADSRPNDSADAAD
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