Gene MMAR_5111 in Mycobacterium marinum M
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namefolP1
Gene length843 bp
IdentifierMMAR_5111
Location 6189644 bp
Protein summary information
Molecular mass29094.0 Da
Isoelectric point5.44
Protein length281 amino acids
Structural information
PFAMB2HJ52
Orthologs
M. tuberculosis H37RvRv3608c
Cross-references
UniProtB2HJ52
Gene OntologyDihydropteroate synthase activity, Folic acid-containing compound biosynthetic process
Precomputed results
BLASTReport
General annotation
TypeCDS
Functioninvolved in dihydrofolate biosynthesis (at the second step). catalyzes the formation of the immediate precursor of folic acid. it is implicated in resistance to sulfonamide [catalytic activity: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + 4-aminobenzoate = pyrophosphate + dihydropteroate].
Productdihydropteroate synthase 1 FolP1
Comments-
Functional categoryIntermediary metabolism and respiration
Coordinates
TypeStartEndOrientation
CDS61896446190486-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium marinum M|MMAR_5111|folP1
VSSRPVQVMGVLNVTNDSFSDGGRYCDEAKAIEHGLALAAEGADIIDVGGESTRPGAARVDPAVEASRVLPVIKELAARGIKVSIDTTRAAVACEALHNGAQIVNDVSGGRADPAMAPLVAEAGVPWVLMHWRPVSDDNPHQVPNYRDVVAEVRAELLTAVDDAIAAGVGPSNLMIDPGLGFAKAGQHNWTLLHALPELVATGIPVLVGASRKRFLGSLLAGPDGAVRPPDGRETATAVISALAALHGAWGVRVHDVRASVDALKVVDAWQRAERTGHDG
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