Gene MMAR_5222 in Mycobacterium marinum M
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameask
Gene length1266 bp
IdentifierMMAR_5222
Location 6307579 bp
Protein summary information
Molecular mass44443.8 Da
Isoelectric point5.04
Protein length422 amino acids
Structural information
PFAMB2HKD0
Orthologs
M. tuberculosis H37RvRv3709c
Cross-references
UniProtB2HKD0
Gene OntologyAmino acid binding, Aspartate kinase activity, Cellular amino acid biosynthetic process
Enzyme Classification2.7.2.4
Precomputed results
BLASTReport
General annotation
TypeCDS
Functioninvolved at the first step in the common biosynthetic pathway leading from asp to the cell wall precursor meso-diaminopimelate, to lys, to met, to ile and to the[catalytic activity: ATP + l-aspartate = ADP + 4-phospho-L-aspartate]. possibly acts in tetramer configuration, tetramer consisting of two alpha (catalytic activity) and two beta (function not known) chains.
Productaspartate kinase Ask
Comments-
Functional categoryIntermediary metabolism and respiration
Coordinates
TypeStartEndOrientation
CDS63075796308844-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium marinum M|MMAR_5222|ask
VALVVQKYGGSSVGNAERIRRVAERIVETKKQGNDVVVVVSAMGDTTDDLMDLALQVCPVPPPRELDMLLTAGERISNALVAMAIESLGAHARSFTGSQAGVITTGTHGNAKIIEVTPGRLQAALDEGRIVLVAGFQGVSQDSKDVTTLGRGGSDTTAVALAAALGADVCEIYTDVDGIFSADPRIVHNARKLDTVTFEEMLEMAACGAKVLMLRCVEYARRHNIPVHVRSSYSDKPGTLVVGSIKDIAMEDPILTGVAHDRSEAKVTIVGIPDIPGYAAKVFRAVAEADVNIDMVLQNVSKVEDGRTDITFTCSRDSGPTAVAKLDLLKDEVGFTQLLYDDHIGKLSLIGAGMRSHPGVTATFCEALAAVGVNIELISTSEIRISVLCRDTELDKAVVALHEAFGLGGEETATVYAGTGR
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