Gene MSMEG_4185 in Mycobacterium smegmatis MC2-155
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namemetH
Gene length3741 bp
IdentifierMSMEG_4185
Location 4261269 bp
Protein summary information
Molecular mass136997.0 Da
Isoelectric point4.5464
Protein length1246 amino acids
Orthologues
M. tuberculosisRv2124c
Cross-references
UniProtA0QZX6
Gene OntologyCobalt ion binding, Dihydropteroate synthase activity, Folic acid-containing compound biosynthetic process, Homocysteine s-methyltransferase activity, Intracellular, Methionine biosynthetic process, Methionine synthase activity, Cobalamin binding
Enzyme Classification2.1.1.13
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
Productmethionine synthase
Commentsidentified by match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607; match to protein family HMM PF02965; match to protein family HMM TIGR02082
Functional categoryUnknown
Coordinates
TypeStartEndOrientation
CDS42612694265009-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium smegmatis MC2-155|MSMEG_4185|metH
MNAVRSETLAPNIRPDCTDALTAALRQRILVIDGAMGTAIQRDRPDEAGYRGERFKDWPSDLVGNNDLLNLTQPHIIEAIHREYLDAGADLLETNTFNANAVSLSDYGMQELAYELNYAGAALARAACDEYSTPDKPRYVAGALGPTTRTASISPDVNDPGARNVSYDQLAEAYLEAARGLVDGGADLIIVETIFDTLNAKAAIFAIETLFEERGRRWPVIISGTITDASGRTLSGQVTEAFWNSIRHAQPLAVGLNCALGAPEMRPYIAEMSRIADTFVSCYPNAGLPNAFGEYDESPKRQASYVEEFAEAGFVNLVGGCCGTTPAHIAEIAKVVEGKPPRQVPEIPVATRLSGLEPLNIDEDSLFVNIGERTNITGSARFRNLIKAEDYDTALSVALQQVEVGAQVIDINMDEGMIDGVAAMDRFTKLIASEPDISRVPVMIDSSKWEVIEAGLKNVQGKPIVNSISLKEGEEKFVREARLCRKYGAAVVVMAFDEQGQADNLERRKQICGRAYKTLTEEVGFPAEDIIFDPNCFALATGIEEHATYGIDFIEACRWIKENLPGVHISGGISNVSFSFRGNNPVREAIHAVFLFHAIKAGLDMGIVNAGALVPYDSIDPELRERIEDVVLNRREDAAERLLEIAERFNSKDKGEDPAAAEWRSLPVRERITHALVKGIDAHVDDDTEELRAEIAAAGGRPIEVIEGPLMDGMNVVGDLFGSGKMFLPQVVKSARVMKKAVAYLLPYIEAEKKPGDAERSNGTIIMATVKGDVHDIGKNIVGVVLQCNNYTVIDLGVMVPAQKILDAAKEHNADIIGLSGLITPSLDEMVNFAAEMEREGMDIPLLIGGATTSRAHTAVKVAPRRSGPVVWVKDASRSVPVAAALLDDKQRPALLEATEKDYASLRERHAQKNERPMVTLEKARANRTPIDWDGYTPPVPAQGLGIREFENYDLSELRQYIDWQPFFNAWEMKGKFPDILNNPASGEAARKLYEEAQEMLDTLIKEKWLTANGVIGFFPANAVGDDIEVYTDDTRTEVLTTLRNLRQQGEHRDGIPNRSLGDFIAPKETGLADYIGAFAVTAGLGSAEKIAEFKADHDDYSAILLESLADRLAEAFAERMHQRVRTELWAYQPDEELDNEALIAERYRGIRPAPGYPACPEHTEKATLFKLLDVTERTGIELTESMAMWPGAAVSGWYFSHPQSQYFVVGRLAQDQVADYARRKGWTLQEAERWLAPNLGYNPED
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