Gene MSMEG_6157 in Mycobacterium smegmatis MC2-155
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nametopA
Gene length2811 bp
IdentifierMSMEG_6157
Location 6226360 bp
Protein summary information
Molecular mass102499.0 Da
Isoelectric point6.6281
Protein length936 amino acids
Orthologs
M. tuberculosis H37RvRv3646c
Cross-references
UniProtA0R5D9
Gene OntologyDna topoisomerase type i activity, Dna topological change, Dna unwinding involved in dna replication, Atp binding
Enzyme Classification5.99.1.2
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductDNA topoisomerase I
Commentsidentified by match to protein family HMM PF01131; match to protein family HMM PF01751; match to protein family HMM TIGR01051
Functional categoryUnknown
Coordinates
TypeStartEndOrientation
CDS62263606229170-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium smegmatis MC2-155|MSMEG_6157|topA
MAGGDRGSGGTGNVRRLVIVESPTKARKIAGYLGSNYVVESSRGHIRDLPRNAADVPAKFKSEPWARLGVNVDQNFEPLYIVSPEKKSTVTELKGLLKDVDELYLATDGDREGEAIAWHLLETLKPRVPVKRMVFHEITEPAIRNAAENPRDLDIALVDAQETRRILDRLYGYEVSPVLWKKVAPKLSAGRVQSVATRIIVQRERERMAFHSASYWDVTAELDASVSDPSASPPKFTAKLNTVDGRRVATGRDFDSLGQLKRPDEVLVLDEASAGALASGLRGAQLAVTSVEQKPYTRRPYAPFMTSTLQQEAARKLRFSSERTMSIAQRLYENGYITYMRTDSTTLSESAINAARTQARQLYGEEYVHPSPRQYTRKVKNAQEAHEAIRPAGDVFQTPGQLHSALDTDEFRLYELIWQRTVASQMADARGTTLSLRIGGSASSGEQVVFNASGRTITFPGFLKAYVESIDELAGGESDDAESRLPNLTQGQRVDAADLSADGHQTSPPARYTEASLIKALEELGIGRPSTYSSIIKTIQDRGYVQKKGSALVPSWVAFAVVGLLEQHFGRLVDYDFTAAMEDELDEIANGQEQRTNWLNNFYFGGEHGVEGSIARAGGLKQLVGGNLEGIDAREVNSIKVFDDSEGRPVYVRVGRNGPYLERMVDDPDNPGEQKPQRANLKEDLTPDELTPELAEKLFATPQEGRSLGIDPETGHEIVAKDGRFGPYVTEVLPEPEDGGDDGTAGTPAKKGKKPTGPKPRTGSLFRSMDLETVTLEDALKLLSLPRVVGVDPTTNEEITAQNGRYGPYLKRGTDSRSLATEDQIFTITLDEALKIYAEPKRRGRQAASAPPLRELGNDPVSGKPMVIKDGRFGPYVTDGETNASLRKGDDVLTITDERASELLADRRARGPVKKKAPAKKAAKKAPAKKAAAKKA
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