Go to browser
virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionPossible methyltransferase
ProductPossible S-adenosylmethionine-dependent methyltransferase
CommentsRv3399, (MTCY78.29c), len: 348 aa. Possible S-adenosylmethionine-dependent methyltransferase (see Grana et al., 2007), similar to other Mycobacterium tuberculosis (strains H37Rv and CDC1551) hypothetical proteins e.g. P95074|Rv0726c|MTCY210.45c (367 aa), FASTA scores: opt: 1188, E(): 7.7e-69, (60.05% identity in 308 aa overlap); MTCY31.21c (38.0% identity in 308 aa overlap), MTV041_5, MTCY4C12_14, MTY13D12_21, MTV043_22, MTCY210_44, MTCI5_19, MTCI5_20, MTV035_9, MTCY180_22, MTCY31_23, MTY13D12_1, MTCY180_29; etc.
Functional categoryLipid metabolism
ProteomicsIdentified by mass spectrometry in whole cell lysates of M. tuberculosis H37Rv but not the culture filtrate or membrane protein fraction (See de Souza et al., 2011).
MutantNon-essential gene for in vitro growth of H37Rv, by analysis of saturated Himar1 transposon libraries (see DeJesus et al. 2017). Non essential gene by Himar1 transposon mutagenesis in H37Rv strain (see Sassetti et al., 2003).
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS38161293817175+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium tuberculosis H37Rv|Rv3399|Rv3399
MARPMGKLPSNTRKCAQCAMAEALLEIAGQTINQKDLGRSGRMTRTDNDTWDLASSVGATATMIATARALASRAENPLINDPFAEPLVRAVGIDLFTRLASGELRLEDIGDHATGGRWMIDNIAIRTKFYDDFFGDATTAGIRQVVILAAGLDTRAYRLPWPPGTVVYEIDQPAVIKFKTRALANLNAEPNAERHAVAVDLRNDWPTALKNAGFDPARPTAFSAEGLLSYLPPQGQDRLLDAITALSAPDSRLATQSPLVLDLAEEDEKKMRMKSAAEAWRERGFDLDLTELIYFDQRNDVADYLAGSGWQVTTSTGKELFAAQGLPPFADDHITRFADRRYISAVLK