Gene ML0047c
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | ESX CONSERVED COMPONENT ECCD1. PROBABLE TRANSMEMBRANE PROTEIN. |
| Comments | ML0047c, len: 512 aa. esx conserved component, probable transmembrane protein, highly similar to M. tuberculosis probable membrane proteins e.g. Rv3877|O69741|AL123456 transmembrane protein (511 aa), Fasta scores: 74.0% identity in 512 aa overlap. Similarity is weaker to Rv1795|O53944|AL123456 probable membrane protein (503 aa), Fasta scores: E(): 2.1e-13, (22.7% identity in 519 aa overlap) and Rv0290|O86362|AL123456 hydrophobic protein (472 aa), Fasta scores: E(): 2.4e-11, (26.6% identity in 512 aa overlap). Also similar to ML1539 and ML2529 from M. leprae. Previously sequenced as O33081|Y14967 (480 aa), Fasta scores: E(): 0, (100.0% identity in 480 aa overlap). Contains hydrophobic, possible membrane-spanning regions. |
| Functional category | Cell wall and cell processes |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 58020 | 59558 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML0047c|eccD1
LSAPAVTAGPATAGITPARPSATRVTILTGKRMTDLVLPSTVSIEAYIDETVAVLSDLLEDAPADVLAGFDFSAQGVWTFARPGSPPMKLDQSLDDAGVVDGSLLTLVSTSRTERYRPLVEDVIDAIAVLNESPEFNRKAVDRFIGVAIPVLSLPITAVAVWAWWVTGRSPFWSLAIGILSIVALTGSIVAEKFYKNLDLSESLLLTSYPLIASAAALVTPLPNGVDSLGPPQVAAAAAAVLFLTLLTRGGARRHSGYASFTAITTIAIVVIAIAYGFGYQHWVPTGAVAFGLFIVTNAAKLTVAVARIALPPIPVPGETVDNEELLDPVVTPHEATHEETPTWQAIIASVPDSAVRLTERSSLAKRLLIGYVISGTLILCSGAIAVIVRGHFFAHSLVVAFLLTVVCTFRSRLYAERWCAWALLAAAVVIPTGLTVKLCIWYTQIAWLLLTSYLVAAIIALMVFGATVRVRRVSPVTKRIMELIDGAVVASIIPLLLWIAGVYDMVRNLSF
Bibliography
- [2009]. Systematic genetic nomenclature for type VII secretion systems. Nomenclature Product
