Gene ML0056c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameespH
Gene length510 bp
IdentifierML0056c
Location 70584 bp
Protein summary information
Molecular mass18452.4 Da
Isoelectric point4.04
Protein length170 amino acids
Orthologs
M. tuberculosis H37RvRv3867
M. lepromatosis Mx1-22AMLPM_0056
Cross-references
UniProtQ9CDD6
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductESX-1 SECRETION-ASSOCIATED PROTEIN ESPH
CommentsML0056c, len: 169 aa. ESX-1 secretion-associated protein, similar to several proteins in M. tuberculosis e.g. Rv3867|O06269|AL123456 ESX-1 secretion-associated protein (184 aa), Fasta scores: E(): 1.1e-12, (38.4% identity in 172 aa overlap); and Rv3614c|O69732|AL123456 protein (183 aa), Fasta scores: E(): 1e-20, (48.2% identity in 166 aa overlap). Also similar to ML0407 from M. leprae. Previously sequenced as Q49730|U00015 (216 aa), Fasta scores: E(): 1.7e-13, (40.2% identity in 169 aa overlap.)
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS7058471093-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0056c|espH
VNLLGNDDDNHLASLDFYSANRYYEESLFFDELDGYAPTTPVGIEANDLDVFQSLTEPEEELEVELLAVTNPAKSVSALMNGRVHQVELTDQVTRIGEKKPATEAFVLASLARQKARTSQGTCILDSLQGGGENTTARCELVGLTLNLPTSEQAAAEAEMFSNNILRQK
Bibliography