Gene ML0102 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameaccD4
Gene length1554 bp
IdentifierML0102
Location 131869 bp
Protein summary information
Molecular mass56020.1 Da
Isoelectric point6.36
Protein length518 amino acids
Structural information
PFAMPF01039
Orthologs
M. tuberculosis H37RvRv3799c
M. lepromatosis Mx1-22AMLPM_0102
Cross-references
UniProtQ9CDB0
Gene OntologyLigase activity
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductProbable propyonyl-CoA carboxylase beta chain 4 AccD4 (Pccase)
CommentsML0102, len: 517 aa. Probable accD4, propyonyl-CoA carboxylase beta chain 4 (EC 6.4.1.3), highly similar to many e.g. Rv3799c|O53578|AL123456 probable accD4, propyonyl-CoA carboxylase from M. tuberculosis (522 aa), Fasta scores: E(): 0, (91.2% identity in 512 aa overlap); and Q9X4K7|AF113605 propionyl-CoA carboxylase complex B subunit from Streptomyces coelicolor (530 aa), Fasta scores: E(): 0, (48.2% identity in 521 aa overlap). Also similar to ML0731 and ML1657 from M. leprae. Contains Pfam match to entry PF01039 Carboxyl_trans, Carboxyl transferase domain.
Functional categoryLipid metabolism
Coordinates
TypeStartEndOrientation
CDS131869133422+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0102|accD4
MIMKSTAEKLAELRVRLELANEPGGEKAAAKRDKKNIPSARARIYALVDPGTFLEIGALTRTPGDPNALYGDGVVTGHGLINGRQVGVFSHDQTVFGGTVGEMFGRKVARLMEWCAMAGCPIVGINDSGGARIQDAVTSLAWYAELGRRHELLSGIVPQISIVLGKCAGGAVYSPIQTDLVVAVRGQGYMFVTGPDVIKDVTGEEVSLDELGGVDSQAKYGNIHQVVESEAAAFGYVRDFLSFLPPNCFDKAPIVNPGLEPEIMAHDLELDSIVPDSDNTAYDMREVLLRIFDDGHFLDVAAQAGQAIITGYARVDGRTVGVVANQPMHLSGAIDNEASDKAARFIRFCDAFNIPLVFVVDTPGFLPGVEQEKNGIIKRGGRFLYAVVEADVPKVTITIRKSYGGAYAVMGSKQLAADLNFAWPTARIAVIGADGAAQLLMKRFPDPSSPDVQAIRKTFVDNYNLNMAIPWIAAERGFIDAVVEPHQTRLLLRKSLHLLRDKQQWWRVGRKHGLIPL
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