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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPossible enoyl-CoA hydratase EchA21 (enoyl hydrase) (unsaturated acyl-coA hydratase) (crotonase)
CommentsML0120c, len: 278 aa. Possible echA21, enoyl-CoA hydratase (EC 4.2.1.17), highly similar to Rv3774|P75019|AL123456 possible echA21, enoyl-CoA hydratase from M. tuberculosis (274 aa), Fasta scores: E(): 0, (88.3% identity in 274 aa overlap); and similar to many others e.g. ECH1_RAT|Q62651 ech1, delta3,5-delta2,4-dienoyl-coa isomerase precursor from Rattus norvegicus (327 aa), Fasta scores: E(): 3.5e-31, (38.8% identity in 276 aa overlap). Also shows some similarity to bacterial putative enoyl-CoA hydratases. And similar to ML1241, ML1724, ML2118 and ML2402 from M. leprae. Contains Pfam match to entry PF00378 ECH, Enoyl-CoA hydratase/isomerase family.
Functional categoryLipid metabolism
Coordinates
TypeStartEndOrientation
CDS161741162577-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML0120c|echA1
MGSDINRAYESVAVEIKDRVAQVTLIGPGKGNAMGPAFWSEMPEVFAELDTNREVRAVVITGSGKDFSYGLDVPAMGGKFVPLLTDGALARPRTDFHAEVLRMQKAINAVADCRTPTIAAVHGWCIGGALDLISAVDIRYASADAKFSMREVKLAIVADMGSLARLPLILSDGHLRELALTGKDIDATRAEKIGLVNDVYDNADKTLAAAHATAAEIAANPPLAVYGVKDVLYQQRTSAISESLRYVAAWNAAFLPSKDLTEGISATFAKRAPQFIGE
      
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