Gene ML0127 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML0127
Gene length690 bp
IdentifierML0127
Location 170662 bp
Protein summary information
Molecular mass26203.0 Da
Isoelectric point5.35
Protein length230 amino acids
Structural information
PFAMPF04989
Orthologs
M. tuberculosis H37RvRv2959c
M. lepromatosis Mx1-22AMLPM_0127
Cross-references
UniProtQ9CD89
Gene OntologyMethyltransferase activity, Lipid biosynthetic process
Enzyme Classification2.1.1.-
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPossible methyltransferase
CommentsML0127, len: 229 aa. Possible methyltransferase (EC 2.1.1.-), highly similar to Rv2959c|Q50457|AL123456 Possible methyltransferase from M. tuberculosis (245 aa), Fasta scores: E(): 0, (76.1% identity in 226 aa overlap). Shows weak similarity to O85726|AF073896 cmcI, cephalosporin hydroxylase component of 7 alpha-cephem-methoxylase from Streptomyces clavuligerus (236 aa), Fasta scores: E(): 0.0001, (27.6% identity in 163 aa overlap ); and to other hypothetical proteins.
Functional categoryIntermediary metabolism and respiration
Coordinates
TypeStartEndOrientation
CDS170662171351+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0127|ML0127
MERVRQMFSCVSGMIYRPTDSIAEEYHKWYYGNFVWNTTTWMGIKCLKSVSDMWNYQEILIELEPSLVIEFGSRFGGSALFFANVMMHIGQPFKVLSVDISHKDLDPAARQPDILFIESPSTAPAIAEQIRRLKNEYPGKIFAILDSDHSMKQVLAEMKLLQPLLTAGDYLVVEDSNLNGHPVLPRFGAGPYEAIEAYEREFPGDYEHDVAREKKFGFTFATNGFLIRK
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