Gene ML0201c
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | Probable conserved transmembrane protein |
| Comments | ML0201c, len: 530 aa. Probable conserved transmembrane protein, highly similar to Rv3645|O06362|AL123456 probable transmembrane protein from M. tuberculosis (549 aa), Fasta scores: E(): 0, (85.3% identity in 530 aa overlap); and to several other putative membrane proteins from M. tuberculosis. Shares regions of similarity with adenylate cyclases e.g. P94180|D89622 cyaA, adenylate cyclase from Anabaena sp. (strain PCC 7120) (735 aa), Fasta scores: E(): 1.5e-16, (33.3% identity in 228 aa overlap). Previously sequenced as O69547|AL023093 (530 aa), Fasta scores: E(): 0, (99.8% identity in 530 aa overlap). Also similar to ML1948c a possible pseudogene similar to M. tuberculosis Rv3645. Contains hydrophobic, possible membrane-spanning regions. Contains Pfam match to entry PF00672 DUF5, Domain found in bacterial signal proteins. Contains 2 Pfam matches to entry PF00211 guanylate_cyc, Adenylate and Guanylate cyclase catalytic domain. |
| Functional category | Cell wall and cell processes |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 268857 | 270449 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML0201c|ML0201c
VATQAAGLPGRIGAFVRWGIRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDRVELQDLPIRNLAISTLSVVVAFSTGFAVNLKLLMPVFRWQRRDNRLAEADPAATELARSRALRMPFYHTIISLVTWGIGGAVFIIASWSAARHSAPIVALATALGATATAIIGYLQSERVLRPVAVAALRSGVPENVKTPGVTLRLMLTWVPSTGVPVLAIVLAVVADKIALLHAVPEQLFSPILLLALAVLVVGLVSTWLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELSERQRLRDLFGRYVGEDVARRALEHGTELGGQERDVAVLFVDLIGSTQLAETKPPTKVVHLLNEFFRVVVDTVGRHGGFVNKFQGDAALAIFGAPIEHPDSAGAALSAARELHDELLPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSGALDAEALCWNVGEIVELRGRTAPTQLARPLNLAVPEQITSEVTG
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