Gene ML0211
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | Possible carboxypeptidase |
| Comments | ML0211, len: 461 aa. Possible carboxypeptidase, highly similar to Rv3627c|O06380|AL123456 hypothetical ala-rich protein from M. tuberculosis (461 aa), Fasta scores: E(): 0, (76.0% identity in 462 aa overlap). Shows weak similarity to penicillin-binding proteins e.g. O85665|AF071224 pbp3, penicillin binding protein 3 from Neisseria gonorrhoeae (469 aa), Fasta scores: E(): 4.5e-08, (33.1% identity in 163 aa overlap). Also similar to putative carboxypeptidases from Streptomyces coelicolor e.g. Q9X8I8|AL049841 SCE9.15C, possible penicillin-binding protein (459 aa), Fasta scores: E(): 3.8e-32, (36.3% identity in 435 aa overlap). Previously sequenced as O69539|AL023093 (461 aa), Fasta scores: E(): 0, (99.8% identity in 461 aa overlap). Also similar to ML2215 a possible pseudogene similar to M. tuberculosis Rv3627c. Contains a possible N-terminal signal sequence. Contains Pfam match to entry PF02113 Peptidase_S13, D-Ala-D-Ala carboxypeptidase 3 (S13) family. |
| Functional category | Cell wall and cell processes, Conserved hypotheticals |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 282157 | 283542 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML0211|ML0211
LNPIRWQKSYVVVGLAMLAFIIAAVKAATVFTTGGHSTNGARSAVPPPRASTVKPALVPVTETAVVPSVGGLAAALASALADPSLGSFGGRITDAMTAKELWQQQDDMPLVPASANKLLTAAAALLTLDRQTRISTRVVAAGPNAQGPVVLVGAGDPTLSAASPDQSTWYRGAPRISDLVEQVRRSGVTPTAVQVDTSLFTGPTMAQGWDPADVDNGYTAPIESAMIDAGRIQPTTVKSRRSRTPALDAGRELAKALGVAPDAVTIVKASSGARQLAVVQSAPLVQRLSEMMDNSDNVLAECIGREVAAAINRPLSFAGAVDAVTNRLGTAHIDTTGAALVDSSGLSVNNRLTAKTLGGAVQAAAGPDQPVLRALLDLLPIAGGSGTLSDRFLSSATHQGPAGWLRAKTGSLTAINSLVGVVTDRSGRVLTFAFISNDAGPTGRAAMDELATRLWMCGCAT
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