Gene ML0223 (gchA)
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | Probable GTP cyclohydrolase I FolE (GTP-CH-I) |
| Comments | ML0223, len: 205 aa. Probable folE (alternate gene name: gchA), GTP cyclohydrolase I (EC 3.5.4.16), highly similar to Rv3609c|GCH1_MYCTU|O06273 folE, GTP cyclohydrolase I from M. tuberculosis (202 aa), Fasta scores: E(): 0, (82.0% identity in 205 aa overlap). Similar to many others e.g. GCH1_BACSU|P19465 mtrA, GTP cyclohydrolase I from Bacillus subtilis (190 aa), Fasta scores: E(): 0, (59.5% identity in 190 aa overlap). Previously sequenced as GCH1_MYCLE|O69531 (205 aa), Fasta scores: E(): 0, (100.0% identity in 205 aa overlap). Contains Pfam match to entry PF01227 GTP_cyclohydroI, GTP cyclohydrolase I. Contains PS00859 GTP cyclohydrolase I signature 1. Contains PS00860 GTP cyclohydrolase I signature 2. Belongs to the GTP cyclohyrolase I family. |
| Functional category | Intermediary metabolism and respiration |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 296082 | 296699 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML0223|folE
MALLDLGLESTAVPRIRVFDQQRAEAAIRELLYAIGEDPDREGLADTPARVARACRELFSGLYTDPQTVLNTMFDEEHNELVIVKEIPMYSTCEHHLVSFHGVAHIGYLPGADGRVTGLSKIARLVDLYAKRPQVQERLTSQIADALVSKLDPRGVIIVVEAEHLCMAMRGVRKPGAITTTSAVRGQFKTDAASRAEALGLILRK
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