Gene ML0233
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) |
| Comments | ML0233, len: 507 aa. Probable lysS, lysyl-tRNA synthetase 1 (EC 6.1.1.6), highly similar to Rv3598c|SYK_MYCTU|O06284 lysS, probable lysyl-tRNA synthase from M. tuberculosis (505 aa), Fasta scores: E(): 0, (85.4% identity in 501 aa overlap). Similar to many other bacterial lysyl-tRNA synthetases e.g. SYK2_ECOLI|P14825 from Escherichia coli (504 aa), Fasta scores: E(): 0, (38.8% identity in 497 aa overlap). Also similar to the C-terminal half of ML1393 from M. leprae. Contains Pfam match to entry PF00152 tRNA-synt_2, tRNA synthetases class II (D, K and N). Contains PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. Belongs to class-II aminoacyl-tRNA synthetase family. |
| Functional category | Information pathways |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 303740 | 305263 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML0233|lysS
VNADPLETDAALPEQFRIRRDKRARLLAEGRDPYPVAIERTHTLAEVRAAYPDLATDSATDDIVGIAGRVIFARNSGKLCFATLQDGDGTNLQVMISLNKVGSETLDAWKVDVDLGDIVYVHGNVISSRSGELSVLADSWQMVSKSLRPLPVAHKEMSEESRVRQRYVDLIVCPQVRIVAHQRIAVIRAIRTALERRGFLEVETPMLQTLAGGAAARPFVTHSNALDIDLYLRIAPELFLKRCIVGGFDKVFELNRVFRNEGADSTHSPEFSMLETYQTYGTYDDSAVVTREIIQEVADEAIGTRQLQMPDDSVYDIDGEWETIQMYPSLSAVLGEEITPQTSVDRLRAIADRLGRGIGPEILDKPSYGHGRLVEQLWEYTVGNTLSAPTFVKDFPVETTPLTRQHRSIPGVTEKWDLYLRGVELATGYSELNDPVVQRERFGQQVRAAAAEEDEAMALDEEFLAALEYAMPPCTGTGMGIDRLLMSLTGLSIRETVLFPIVRPHSN
Bibliography
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