Gene ML0297c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namethiG
Gene length786 bp
IdentifierML0297c
Location 380645 bp
Protein summary information
Molecular mass27106.1 Da
Isoelectric point4.61
Protein length262 amino acids
Structural information
PFAMPF05690
Orthologues
M. tuberculosisRv0417
Cross-references
UniProtQ9ZBL2
Gene OntologyCytoplasm, Thiamine biosynthetic process, Catalytic activity
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductProbable thiamine biosynthesis protein ThiG (Thiazole biosynthesis protein)
CommentsML0297c, len: 261 aa. Probable thiG, thiamine biosynthesis protein, highly similar to Rv0417|P96263|AL123456 thiG, thiamine biosynthesis protein from M. tuberculosis (252 aa), Fasta scores: E(): 0, (86.8% identity in 250 aa overlap). Similar to many proteins involved in the biosynthesis of the thiazole moiety of thiamine e.g. THIG_ECOLI|P30139 thiG, thiamine biosynthetic protein (thiazole moiety) from Escherichia coli (281 aa), Fasta scores: E(): 0, (51.2% identity in 244 aa overlap). Previously sequenced as Q9ZBL2|AL035159 (261 aa), Fasta scores: E(): 0, (99.6% identity in 261 aa overlap). Belongs to the thiG family.
Functional categoryIntermediary metabolism and respiration
Coordinates
TypeStartEndOrientation
CDS380645381430-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0297c|thiG
VVESKFTIGDRTFTSRLIMGTGGAANLAILEEALIASGTELTTVAIRRVDTDGGSGLLKLLSRLDIMPLPNTAGCRSAAEAVLTAQLAREALNTNWIKLEVIADERTLLPDGLELVRAAEQLVDAGFVVLPYTNDDPALAHRLEGTGCAAVMPLGSPIGTGLGINNPHNIEIIVAQARVPVVLDAGIGTTSDAALAMELGCDAVLLASAVTRAVDPPTMAAAMASAVTAGYLARRAGRIPKRFWAQASSPELMRTGEELGN
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