Gene ML0316
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | Possible transcriptional regulator (TetR family) |
| Comments | ML0316, len: 200 aa. Possible TetR/AcrR-family transcriptional regulator, highly similar except in N-terminus to Rv0067c|O53612|AL123456 possible transcriptional regulator from M. tuberculosis (189 aa), Fasta scores: E(): 0, (68.8% identity in 189 aa overlap). Similar to many putative transcriptional regulators e.g. Q9RJL5|AL121849 putative tetR family transcriptional regulator SCF6.16 from Streptomyces coelicolor (194 aa), Fasta scores: E(): 2.5e-18, (39.5% identity in 185 aa overlap). Previously sequenced as Q9ZBM6|AL035159 (189 aa), Fasta scores: E(): 0, (100.0% identity in 189 aa overlap). Contains a probable helix-turn-helix motif at aa 45-66 (Score 1800, SD +5.32). Contains Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family. Belongs to the tetR/acrR family of transcriptional regulators. |
| Functional category | Regulatory proteins |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 404708 | 405310 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML0316|ML0316
MSVPRSGLSVQMAQPARPLRADAARNRARILGVAYEAFATEGLSVPIDEIARRAGVGAGTVYRHFPTKEALCAAVIGDRMPHLVDDGYVLLKSAGPGEALFTYLRSLVLHWGATDRGLVDALAGAGGIDILGVAPDAEDAFLTILSDLLYAAQYAGTARTDVGVREVKSILVGCQAMEAYNSALAERVTDVVVDGLRAAR
Bibliography
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