Gene Rv0067c in Mycobacterium tuberculosis H37Rv
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameRv0067c
Gene length570 bp
IdentifierRv0067c
Location 74629 bp
Protein summary information
Molecular mass20385.4 Da
Isoelectric point8.4915
Protein length189 amino acids
Structural information
PFAMO53612
Orthologues
M. bovisMb0068c
M. lepraeML0316
M. smegmatisMSMEG_0878
Cross-references
UniProtO53612
Gene OntologyGO:0006350, Sequence-specific dna binding transcription factor activity, Regulation of transcription, dna-dependent
SWISS-MODELO53612
TB databaseRv0067c
Interacting Drugs/Compounds
TDR TargetsLink
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionPossibly involved in transcriptional mechanism.
ProductPossible transcriptional regulatory protein (possibly TetR-family)
CommentsRv0067c, (MTV030.10c), len: 189 aa. Possible transcriptional regulator, highly similar to many. Contains probable helix-turn-helix motif from aa 34 to 55 (Score 1523, +4.37 SD).
Functional categoryRegulatory proteins
MutantNon-essential gene for in vitro growth of H37Rv, by analysis of saturated Himar1 transposon libraries (see DeJesus et al. 2017).
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS7462975198-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium tuberculosis H37Rv|Rv0067c|Rv0067c
LAPTDRRVRADAARNRARVLEVAYQTFAADGLSVPVDEIARRAGVGAGTVYRHFPTKEALFQAVIADRMHRIIDKGHALLKSKHPGDALFAFLRSMVLQWGATDRGLVEALAGVGIEISSAAPEAEADFLDLLTDLLRAAQRAGTVRPDVDVLEVKTLLVGCQAMQSYNAELAAKVTDVALDGLRANRK
Bibliography