Gene ML0348 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML0348
Gene length1053 bp
IdentifierML0348
Location 438263 bp
Protein summary information
Molecular mass37539.8 Da
Isoelectric point4.93
Protein length351 amino acids
Structural information
PFAMPF00296
Orthologs
M. tuberculosis H37RvRv3520c
M. lepromatosis Mx1-22AMLPM_0348
Cross-references
UniProtQ9CCV8
Gene OntologyOxidoreductase activity, Oxidation-reduction process
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPossible coenzyme F420-dependent oxidoreductase
CommentsML0348, len: 350 aa. Possible coenzyme F420-dependent oxidoreductase (EC 1.-.-.-), highly similar to Rv3520c|O53565|AL123456 possible coenzyme F420-dependent oxidoreductase from M. tuberculosis (347 aa), Fasta scores: E(): 0, (86.8% identity in 342 aa overlap). Similar to other coenzyme F420-dependent enzymes (and other proteins) e.g. Q50744|X86477 mer, methylenetetrahydromethanopterin reductase from Methanobacterium thermoautotrophicum (321 aa), Fasta scores: E(): 2.8e-05, (27.1% identity in 332 aa overlap); and Q9AD98|SCI52.11c putative ATP/GTP-binding protein from Streptomyces coelicolor (351 aa).
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS438263439315+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0348|ML0348
LVERANAMKLGLQLGYWAAQPPGNAAELVAAAEGAGFDAVFTGEAWGSDAYTPLAWWGSSTQRVRLGTSVVQLSARTPTACAMAALTLDHLSGGRHILGLGVSGPQVVEGWYGQPFPKPLSRTREYIDIVRQVWAREAPVVSDGQHYPLPLTGAGATGLGKALKPITHPLRADIPIMLGAEGPKNVALAAEICDGWLPIFFSPRMADMYNEWLDEGFARTGARRSREDFEICASAQIVVTEDRAAAFAGIKPFLALYMGGMGAEGTNFHADVYRRMGYAEVVDEVTALFRSNQKDKAAEIIPNELVDSTMIVGDVDYVCKQIAAWSAAGVTMMMVSASSVEQVRDLAGLF
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