Gene ML0375
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | Probable alanine racemase Alr |
| Comments | ML0375, len: 388 aa. Probable alr, alanine racemase (EC 5.1.1.1), highly similar to Rv3423c|ALR_MYCTU|Q50705 alr, probable alanine racemase from M. tuberculosis (408 aa), Fasta scores: E(): 0, (84.6% identity in 382 aa overlap). Highly similar to other alanine racemases e.g. ALR_MYCSM|P94967 alr, alanine racemase from Mycobacterium smegmatis (389 aa), Fasta scores: E(): 0, (67.2% identity in 378 aa overlap); and O86786|ALR_STRCO|SC6G4.23 from Streptomyces coelicolor (391 aa). Previously sequenced as ALR_MYCLE|P38056 (388 aa), Fasta scores: E(): 0, (99.7% identity in 388 aa overlap). Contains 2 Pfam matches to entry PF00842 Ala_racemase, Alanine racemase. Belongs to the alanine racemase family. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 468133 | 469299 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML0375|alr
LAVTPISLRPGVLAEAVVDLGAIDYNVRVLREHAGMAQLMVVLKADAYGHGATQVALAALAAGAAELGVATVDEALALRADGISAPVLAWLHPPGIDFGPALLADVQIAVSSVRQLDELLDAVRRTGRTATVTVKADTGLNRNGVVTDQYPAMLTALQRAVVEDAVRLRGLMSHLVYADQPDNPSNDVQGKRFAALLAQAHEQGLRFEVAHLSNSSATMSRPDLAYDLVRPGIAVYGLSPVPSRGDMGLIPAMTVKCAVAMVKSIRAGEGVSYGHDWIAQHDTNLALLPVGYADGVFRSLGGRLDVLINGKRRPGVGRICMDQFVVDLGPGPIDVAEGDEAILFGPGARGEPTAQDWADLLGTIHYEVVTSLRGRITRTYREAQTVDR
Bibliography
No article yet recorded
