Gene ML0382c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namewhiB3
Gene length309 bp
IdentifierML0382c
Location 475772 bp
Protein summary information
Molecular mass11576.2 Da
Isoelectric point8.68
Protein length103 amino acids
Structural information
PFAMPF02467
Orthologs
M. tuberculosis H37RvRv3416
M. lepromatosis Mx1-22AMLPM_0382
Cross-references
UniProtQ49871
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductProbable transcriptional regulatory protein WhiB-like WhiB3
CommentsML0382c, len: 102 aa. Probable whiB3 (alternate gene name: whmB), WhiB-like regulatory protein (see citations below), highly similar to Rv3416|Q50710|AL123456 whiB3, WhiB-like regulatory protein from M. tuberculosis (102 aa), Fasta scores: E(): 0, (86.3% identity in 102 aa overlap). Similar to many e.g. O88103|AJ010601 whiD, developmental regulatory gene from Streptomyces coelicolor (112 aa), Fasta scores: E(): 1.1e-24, (61.8% identity in 102 aa overlap). Previously sequenced as Q49871|U00015 (102 aa), Fasta scores: E(): 0, (100.0% identity in 102 aa overlap). Also similar to ML0760, ML0804 and ML2307 from M.leprae. Contains Pfam entry to PF02467, Transcription factor WhiB.
Functional categoryRegulatory proteins
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS475772476080-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0382c|whiB3
MPQPKQLPGPNATIWNWQLQGLCRGVDSSMFFHPDGERGRARMQREQRAKEMCRRCPVIEECRAHALDVGEPYGVWGGLSESERDLLLKGDLARSRSIPRSA
Bibliography
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