Gene ML0392c
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | Possible hydrolase |
| Comments | ML0392c, len: 792 aa. Possible hydrolase (EC 3.-.-.-), highly similar to Rv3401|YY01_MYCTU|Q50724 conserved hypothetical protein from M. tuberculosis (786 aa), Fasta scores: E(): 0, (91.4% identity in 782 aa overlap). Similar to other bacterial hydrolases and transferases e.g. Q9L2I8|SCF42.31c putative glycosyl transferase from Streptomyces coelicolor (792 aa), Fasta scores: E(): 0, (58.9% identity in 790 aa overlap); and Q9K109|NMB0390 maltose phosphorylase from Neisseria meningitidis (serogroup B) (752 aa). Previously sequenced as YY01_MYCLE|Q49736 (792 aa), Fasta scores: E(): 0, (100.0% identity in 792 aa overlap). Contains a probable helix-turn-helix motif at aa 515-536 (Score 1032, SD +2.70). Contains Pfam match entry to PF03632; Glyco_hydro_65m, PF03633; Glyco_hydro_65c and PF03636; Glyco_hydro_65n. Belongs to family 65 of glycosyl hydrolases. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 486264 | 488642 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML0392c|ML0392c
MITEEAFPVEPWQIRETRLDLNLLAQSESLFALSNGHIGLRGNLDEGEPYGLPGTYLNSFYEIRPLPYAEAGYGYPEAGQTVVDVTNGKILRLFVEDEPFDVRYGEVIFHERVLDLCAGTLTRRANWRSPADKQVKVVSTRLVSLAHRSVAAIEYVVEALDKFVRVTVQSELVSNEDQPETSGDPRVSAILDNPLEAVEHEATERGGLLMHRTRASSLMMAAGMDHEVEVPGRVEITTDARPDLARTTVICGLRPGQKLRIVKYLAYGWSSLRSRPALHDQATAALHTARYSGWQGLLDAQRAYLNEFWDSADVEVEGDPESQQAVRFGLFHLLQASARAERRAIPSKGLTGTGYDGHAFWDTEGFVLPVLTYTAPHAVADALRWRASTLQLAKDRAAELGLDGASFCWRTIRGQECSAYWPAGTAAWHINADIAMAFERYRIVTGDHSLEEECGLAVLIETARLWLSLGHHDRHGVWHLDGVTGPDEYTAVVRDNVFTNLMAASNLITAADACLRQPEAAKAMGVTTEEMAAWRDAADAANIPYDDELGVHQQCEGFTTFAEWDFEANTTYPLFLHEAYVRLYPAQVIKQADLVLAMQWQSHAFTPEQKARNVDYYERRMVRDSSLSACTQAVMCAEVGHLELAHDYAYEAALIDLRDLHRNTRDGLHMASLAGAWTALVGGFGGLRDDEGILSIDPQLPHGISRLRFRLRWRGFRLTVDARHADVTYTLRDGPGGELTIRHAGEHLTLKSDSPSTIAVRDRKPLLPPPSQPPGREPVSRRHKSLIISAAR
Bibliography
No article yet recorded
