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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductProbable hydrolase
CommentsML0393c, len: 261 aa. Probable hydrolase (EC 3.-.-.-), highly similar to Rv3400|YY00_MYCTU|Q50725 probable hydrolase from M. tuberculosis (262 aa), Fasta scores: E(): 0, (74.4% identity in 262 aa overlap). Similar to several various proteins (notably hydrolases) e.g. Q9L2I7|SCF42.32 PUTATIVE HYDROLASE from Streptomyces coelicolor (246 aa), FASTA scores: opt: 843, E(): 7.6e-47, (51.61% identity in 248 aa overlap); and Q9I5X4|PA0562 PROBABLE HYDROLASE from Pseudomonas aeruginosa (224 aa). Previously sequenced as YY00_MYCLE|Q49741 (261 aa), Fasta scores: E(): 0, (100.0% identity in 261 aa overlap). Contains Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS488656489441-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML0393c|ML0393c
MANWDHPTSKVRSTVLGLPEQVRACLFDLDGVLTDTASVHAKAWQTMFDTYLYQRAKHTGENFVPFDPTADYRQYVDGKKREDGVRSFLGSRGITLPEGSADNSGDVETIYGLGNRKDDLFRQVLKEHGIEVFDGSRRYLEAITYAGLGVAVVSSSTNTRDVLKITGLDRFVQQQVDGITLREEHIAGKPAPDSYLRGAQLLDVAPDAAAVFEDALSGVQAGLSGHFGFVVGINRTGRVDQAEELRRIGANVVVTDLAELL
      
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