Gene ML0407 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameespD
Gene length651 bp
IdentifierML0407
Location 504794 bp
Protein summary information
Molecular mass24227.7 Da
Isoelectric point4.32
Protein length217 amino acids
Orthologs
M. tuberculosis H37RvRv3614c
M. lepromatosis Mx1-22AMLPM_0407
Cross-references
UniProtQ49730
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductESX-1 SECRETION-ASSOCIATED PROTEIN ESPD
CommentsML0407, len: 216 aa. ESX-1 secretion-associated protein, highly similar to Rv3614c|O06269|AL123456 ESX-1 secretion-associated protein from M. tuberculosis (184 aa), Fasta scores: (71.5% identity in 186 aa overlap) and to Rv3867|O69732|AL123456 protein from M. tuberculosis (183 aa), Fasta scores: E(): 2.1e-28, (51.4% identity in 175 aa overlap). Previously sequenced as Q49730|U00015 (216 aa), Fasta scores: (100.0% identity in 216 aa overlap). Also similar to ML0056 from M. leprae.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS504794505444+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0407|espD
MGSRRRINRRLLPMSTFPAWQEFRRDVVVVFPGNDFDRDDCDTVDPWGVGGAAHWTIDPIVGFASSSAPQDRGTDVDNTRGQAEEDEKQKEPEVAIFTVTNPPRTVSVSVLMDGRIDHVELSKRVTWMSESQVASEILVLADLARQKAQSAQYTFILDKLSQLADGDEHRVALLRESVGNTWNLPSPEQAAEAEAEVFATRYSDYCPAQDTENDQW
Bibliography